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NCT Number: NCT07086092

Relationship Between Serum Markers and Motor Recovery and Ambulation in Post-stroke Patients

This study aim to retrospectively investigate the effects of the magnesium, vitamin D, and uric acid serum markers on motor recovery and ambulation in post-stroke patients.

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Key information

Conditions

Stroke Biomarkers Brain Diseases Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Nervous System Diseases Serum Magnesium Serum Uric Acid Serum Vitamin D Vascular Diseases

Age range

30 year–90 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Abant Izzet Baysal University

Bolu, 14100, Turkey (Türkiye)

About this study

Stroke is the sudden loss of neurological function associated with a reduction or cessation of blood flow in the brain, resulting from the blockage or rupture of cerebral vessels. Stroke is the second leading cause of death and the third leading cause of disability worldwide. Regaining motor recovery and ambulation skills in patients is one of the main goals of rehabilitation. It is critical for patients to improve their quality of life and regain their independence. Serum biochemical markers can be used to predict post-stroke recovery. Serum magnesium, vitamin D, and uric acid are biochemical markers that may play a role in the recovery process of stroke patients.

This study aim to retrospectively investigate the effects of the magnesium, vitamin D, and uric acid serum markers on motor recovery and ambulation in post-stroke patients.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients who had a single stroke between 2019 and 2024
  • Patients who were admitted to the rehabilitation ward and had their serum vitamin D, magnesium, and uric acid levels measured
  • Patients whose functional ambulation scale scores and Brunnstrom motor recovery stages were recorded

Exclusion criteria

  • Patients with other neurological diseases
  • Patients with multiple strokes
  • Patients with gout, renal failure, or hyperparathyroidism

Treatment and study plan

Serum magnesium, uric acid, and vitamin D levels and motor recovery and ambulation stages

Other

Serum magnesium, uric acid, and vitamin D levels, as well as motor recovery and ambulation levels, measured during the patients' rehabilitation stay will be obtained from past medical records.

Primary outcomes

  1. Serum magnesium levels

    Time frame: Before treatment

    Serum magnesium levels measured before the patients' rehabilitation will be obtained from past medical records.

  2. Serum uric acid levels

    Time frame: Before treatment

    Serum uric acid levels measured before the patients' rehabilitation will be obtained from past medical records.

  3. Serum vitamin D levels

    Time frame: Before treatment

    Serum vitamin D levels measured before the patients' rehabilitation will be obtained from past medical records.

  4. Brunnstrom Motor Recovery Stage

    Time frame: Before treatment

    Brunnstrom stages is a scale used to assess motor recovery after a stroke, which is expressed using values between 1 and 6. The higher the value on this scale, the higher would be the recovery. Brunnstrom Motor Recovery Stages measured before the patients' rehabilitation will be obtained from past medical records.

  5. Functional Ambulation Classification

    Time frame: Before treatment

    Functional Ambulation Classification is a 6-point functional walking test that evaluates ambulation ability and determines the amount of human support required by patients while walking, regardless of whether they use a personal assistive device. A score of 0 indicates that the patient has a dysfunctional ambulation A score of 5 denotes independent ambulation on any surface. Functional Ambulation Classification Stages measured before the patients' rehabilitation will be obtained from past medical records.

Sponsors and collaborators

Lead sponsor

Abant Izzet Baysal University

Other

Registry information

Official study title

Relationship Between Serum Markers and Motor Recovery and Ambulation in Post-stroke Patients: a Retrospective Analysis

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jul 25, 2025
Registry last updated
Jul 29, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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