Relationship Between Repetitive Negative Thinking and CBT Outcomes

The goal of this observational study is to learn about the role of repetitive negative thinking (measured by the RTQ) in adult populations from an anxiety disorders and trauma clinic.

The main questions it aims to answer are:

* Whether the repetitive negative thinking can be used to predict i. initial symptom severity, and ii. therapy outcome (measured by change in scores on disorder specific measures). * Whether change in RTQ mediates change in outcome Participants are sent weekly questionnaires that measure their progress. Within these questionnaires are the RTQ and other disorder-specific measures that we will be analysing.

Researchers may also compare clients with different disorders to see the accuracy the RTQ can predict treatment outcomes for each disorder.

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Key information

Conditions

Anxiety Disorders Body Dysmorphic Disorders Digestive System Diseases Feeding and Eating Disorders Gastrointestinal Diseases Mental Disorders Obsessive-Compulsive Disorder Panic Disorder Phobia, Social Phobia, Specific Phobic Disorders Post-traumatic Stress Disorder Rumination Syndrome Social Anxiety Disorder Somatoform Disorders Specific Phobia Stress Disorders, Post-Traumatic Stress Disorders, Traumatic Trauma and Stressor Related Disorders

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Centre for Anxiety Disorders and Trauma

London, SE5 8AZ, United Kingdom

About this study

We are looking to examine how repetitive negative thinking (RNT; i.e. rumination and worry), measured by the repetitive thinking questionnaire (RTQ), affects the outcomes of Cognitive Behavioural Therapy (CBT) for anxiety and trauma disorders. Our study will involve looking over data collected from clients who completed treatment at the Centre for Anxiety Disorders and Trauma (CADAT) from 01/01/2022 to 31/03/2024, we will look at data from before they started treatment, whilst in treatment and once they completed treatment. This is an important issue to address as there is little guidance within existing CBT protocols on to how to identify and target RNT during treatment. Evidence also suggests that not only does RNT maintain anxiety disorders, but it can also interfere with therapy outcome. Research has found that patients receiving CBT for PTSD who displayed high-levels of rumination within their early CBT sessions had poorer outcomes in therapy. Our aim is to formally analyse the relationship between scores on the RTQ and both symptom severity and CBT treatment outcome for anxiety disorders. This would help us to test our hypotheses about the relationship (i.e. those with high RNT have poorer treatment outcomes and changes in RNT predict outcome across a range of anxiety and trauma disorders) and provide a basis for augmenting our existing treatments with interventions that specifically target this process.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Participants must have completed a course of CBT treatment at CADAT for one of the following anxiety disorders: OCD, PTSD, Panic Disorder, Health Anxiety, Emetophobia, Specific Phobia, Social Phobia, BDD, GAD, DPD or Hoarding.
Participants must have completed regular questionnaires throughout their treatment.

Exclusion criteria

Participants who dropped out of treatment
Participants who did not complete online questionnaires.

Treatment and study plan

Primary outcomes

Change in Repetitive Ruminative Thinking Questionnaire score

Time frame: From pre treatment to post treatment for CBT at CADAT (an average of 12-20 weeks)

Change in RTQ from pre- to post-treatment
Change in disorder-specific measure score

Time frame: From pre treatment to post treatment for CBT at CADAT (an average of 12-20 weeks)

Change in disorder-specific measure scores from pre- to post-treatment

Sponsors and collaborators

Lead sponsor

South London and Maudsley NHS Foundation Trust

Other

Registry information

Official study title

The Relationship Between Repetitive Negative Thinking (RNT) and CBT Treatment Outcome Within a Specialist Anxiety Disorders Clinic.

Important dates

Study start: 2022
Primary completion: 2024
Study completion: 2024
First posted: Apr 17, 2024
Registry last updated: Apr 17, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed