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NCT Number: NCT06647771

Relationship Between Postoperative Tempeartive and Acute Kidney Injury

The investigators aimed to identify body temperature trajectory classes based on core temperature changes during the first 12 hours post-surgery and to explore their relationship with postoperative acute kidney injury in patients undergoing valvular heart surgery.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Patients Undergoing Valvular Heart Surgery

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine

Seoul, South Korea

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients who underwent valvular heart surgery between January 2016 and July 2023 at Severance Cardiovascular Hospital of Yonsei University Health System

Exclusion criteria

  • Patients who underwent the same surgery within 30 days,
  • Patients with less than two temperature measurements within 12 hours after surgery, - Patients with missing creatinine test values before and within seven days after surgery,
  • Patients who died during surgery

Treatment and study plan

Primary outcomes

  1. acute kidney injury ≥ stage 2 according to the KDIGO criteria

    Time frame: seven days after valvular heart surgery

    According to the KDIGO criteria, postoperative acute kidney injury of stage 2 or higher was defined as a 100% increase in creatinine within the first seven days after surgery. The association between stage 2-3 acute kidney injury and postoperative body temperature trajectory classes was investigated.

Secondary outcomes

  1. non-recovery from acute kidney injury within 48

    Time frame: 72 hours after the onset of acute kidney injury

    The association between postoperative body temperature trajectory classes and non-recovery from acute kidney injury was investigated at two time points: within 48 hours

  2. non-recovery from acute kidney injury within 72 hours

    Time frame: 72 hours after the onset of acute kidney injury

    The association between postoperative body temperature trajectory classes and non-recovery from acute kidney injury was investigated at two time points: within 72 hours.

Sponsors and collaborators

Lead sponsor

Yonsei University

Other

Registry information

Official study title

Relationship Between First 12-h Body Temperature and Acute Kidney Injury After Valvular Heart Surgery

Important dates

Study start
2024
Primary completion
2026
Study completion
2026
First posted
Oct 18, 2024
Registry last updated
Oct 18, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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