Skip to main content
OpenTrials
Completed

NCT Number: NCT04284475

Relationship Between Muscle Strength and Physical Function in ICU

This observational study aims to assess the relationship between muscle strength and physical function in critical ill patients. Grip and quadriceps strengths are measured using a standardized protocol of dynamometry. Physical function is assessed using the validated ICU mobility scale.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Critical Illness Disease Attributes Muscle Weakness Muscular Diseases Musculoskeletal Diseases Nervous System Diseases Neurologic Manifestations Neuromuscular Manifestations Pathologic Processes Pathological Conditions, Signs and Symptoms Physical Dependence Physical Disability Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University Hospital of Liège

Liège, 4000, Belgium

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • ICU stay of at least 48h
  • Collaborative (RASS score -1 to +1)

Exclusion criteria

  • Refusal
  • Coma
  • Non collaborative
  • Hemi / tetra paresis or plegia

Treatment and study plan

Quadriceps strength

Diagnostic Test

Using a handheld dynamometer, in supine position in a standardized position of the dominant leg Measurement of the maximal isometric voluntary quadriceps contraction Measure expressed as Newton and Newton/kg

Grip strength

Diagnostic Test

Testing of dominant hand using a handgrip Measurement of the maximal isometric voluntary grip contraction Measure is expressed as kg

ICU mobility scale

Diagnostic Test

Scoring the physical capacity of the patient on a 10-points validated scale: the ICU mobility scale

Primary outcomes

  1. Quadriceps strength

    Time frame: as soon as collaborative during ICU stay and up to 1 month following ICU discharge

    Quadriceps maximal isometric strength measured using dynamometry

  2. Handgrip strength

    Time frame: as soon as collaborative during ICU stay and up to 1 month following ICU discharge

    Grip maximal isometric strength measured using dynamometry

  3. ICU mobility scale

    Time frame: as soon as collaborative during ICU stay and up to 1 month following ICU discharge

    Ranking the patient on the scale according to his/her physical capacity. ICU mobility scale is a 10 points scale: 0 means the patient is lying in bed, 10 means the patient is able to walk independently

Sponsors and collaborators

Lead sponsor

University of Liege

Other

Registry information

Official study title

Analysis of the Relationship Between Muscle Strength and Physical Function in ICU Survivors

Important dates

Study start
2018
Primary completion
2019
Study completion
2021
First posted
Feb 25, 2020
Registry last updated
Nov 26, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.