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Completed

NCT Number: NCT07419750

Relationship Between Muscle Strength and Balance

This study aims to examine the relationship between lower extremity muscle strength and balance and to compare these parameters between healthy individuals and individuals with lower extremity injuries.

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Key information

Conditions

Healthy Anterior Cruciate Ligament Injuries Anterior Cruciate Ligament Injury Balance Chronic Ankle Instability, CAI Knee Injuries Leg Injuries Muscle Strengh Wounds and Injuries

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Biruni University

Istanbul, Zeytinburnu, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Anterior Cruciate Ligament (ACL) Injury Group:

  • Aged between 18 and 40 years
  • Diagnosed with a unilateral ACL injury 6 to 18 months prior to participation
  • Diagnosis confirmed by magnetic resonance imaging (MRI)
  • Ability to speak, read, and understand Turkish
  • Willingness to participate voluntarily in the study

Chronic Ankle Instability (CAI) Group:

  • Aged between 18 and 40 years
  • Diagnosed with chronic ankle instability due to recurrent ankle sprains 6 to 18 months prior to participation
  • History of at least two ankle sprains
  • Ongoing symptoms of functional ankle instability (e.g., episodes of giving way, feelings of instability)
  • Ability to speak, read, and understand Turkish
  • Willingness to participate voluntarily in the study

Healthy Control Group:

  • Aged between 18 and 40 years
  • No history of lower extremity injury or orthopedic diagnosis
  • Ability to speak, read, and understand Turkish
  • Willingness to participate voluntarily in the study

Exclusion criteria

  • Presence of neurological, vestibular, or visual disorders that may affect balance
  • History of other orthopedic diseases or trauma
  • Presence of musculoskeletal disorders or cardiovascular comorbidities
  • History of physiotherapy, rehabilitation, or surgical intervention within the past 6 months

Treatment and study plan

Primary outcomes

  1. Static Balance Performance-ALFA Stabilometric Platform

    Time frame: Baseline

    Static balance performance will be assessed using the ALFA Stabilometric Platform. A static balance performance score generated by the device software will be recorded separately for each side during the assessment. Higher scores indicate better static balance performance.

Secondary outcomes

  1. Dynamic Balance Performance-ALFA Stabilometric Platform

    Time frame: Baseline

    Dynamic balance performance will be assessed using the ALFA Stabilometric Platform. The device software calculates an overall dynamic balance performance score based on center of pressure control during a visually guided task. Higher scores indicate better dynamic balance performance.

  2. Isokinetic Muscle Strength

    Time frame: Baseline

    Isokinetic muscle strength will be assessed using an isokinetic dynamometer. Peak torque values of the knee extensor (quadriceps) and flexor (hamstrings), as well as ankle plantar flexor and dorsiflexor muscle groups, will be recorded.

  3. Isokinetic Muscle Endurance

    Time frame: Baseline

    Isokinetic muscle endurance will be assessed using an isokinetic dynamometer. Endurance-related parameters of the knee extensor (quadriceps) and flexor (hamstrings), as well as ankle plantar flexor and dorsiflexor muscle groups, will be recorded during repeated contractions.

  4. Pain Intensity

    Time frame: Baseline

    Pain intensity during activity will be assessed using the Visual Analog Scale (VAS). The scale ranges from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. Higher scores indicate greater pain intensity.

  5. Kinesiophobia

    Time frame: Baseline

    Fear of movement will be assessed using the Tampa Scale for Kinesiophobia. The total score ranges from 17 to 68, with higher scores indicating greater fear of movement.

Sponsors and collaborators

Lead sponsor

Biruni University

Other

Registry information

Official study title

Relationship Between Muscle Strength and Balance: A Comparison Between Healthy Individuals and Those With Lower Extremity Injuries

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Feb 19, 2026
Registry last updated
Mar 24, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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