Skip to main content
OpenTrials
Recruiting

NCT Number: NCT07687303

Relationship Between Mechanical Ventilator's Modes , Intra-Abdominal Pressure, Mechanical Power and Gastric Tube Tolerance Among Mechanically Ventilated Patients.

The study aims to:

Explore the relationship between MV modes on the IA, MP and GT tolerance among mechanically ventilated patients.

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Intra Abdominal Pressure Mechanical Power

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Observational

Primary location

About this study

Modes of MVs by means of their differential effect on intra-thoracic pressure can have a significant influence on IAP. An ideal ventilation mode could optimize respiratory mechanics and may protect a variety of body systems functions. Among the many MV modes, SIMV, BIPAP and CPAP are the three most used modes

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • adult patients requiring MV in ICU

Exclusion criteria

  • patients with abdominal or chest trauma,
  • patients with intra abdominal pathologies,
  • patients who had received more than 10 units of red blood cells or more than 5 liters of intravenous liquids over the last 24 h,
  • patients with sepsis or hepatic, or renal dysfunction,
  • patients in positions other than supine, and
  • body mass index (BMI) ≥ 30 kg/m2.

Treatment and study plan

Primary outcomes

  1. intra-abdominal pressure "IAP"

    Time frame: day 1

    IAP will be measured through foly catheter

  2. mechanical power

    Time frame: day 1

    it will be: MP (J/ min) =0.098×RR×Vt × [Peak Pressure-(DP/2)] measured through folly catheter

  3. gastric tube tolerance

    Time frame: day 1

    The GT tolerance will be presented as yes if the patient was on GT feeding, and no, if the patient had delayed gastric emptying and converted to gastric drain

Study contacts

Contact information is provided by the study sponsor or research team.

Alaa Mustafa assistant professor, assistant professor

CONTACT

[email protected]

0201097210526

heba attia lecturer, lecturer

CONTACT

[email protected]

045 01274855242

Sponsors and collaborators

Lead sponsor

[email protected]

Other

Registry information

Acronym: MV and IAP

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jul 7, 2026
Registry last updated
Jul 7, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.