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NCT Number: NCT04660487

Relationship Between "FODMAPs" and "GVHD"

With the stem cell transplanting increasing, patients which effected with "GVHD" were also increased. To evaluation the relationship between "FODMAPs" and "GVHD", Bone marrow transplant patients were recruited.

Recruiting

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Key information

Conditions

Graft Versus Host Disease Graft vs Host Disease Immune System Diseases

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Observational

Primary location

About this study

The feces were collected from the patients who had been successfully transplanted after bone marrow transplantation. After 24 hours of culture in the culture medium, the degradation rate of "FODMAPs" was detected, and the relationship between the degradation rate and the occurrence time and degree of "GVHD" was observed

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Clinical diagnosis of "AML","ALL","MDS" or "MM" Disease;
  • Must be treated with bone marrow transplantation;
  • The transplanted bone marrow was successfully planted

Exclusion criteria

  • Gastrointestinal diseases；
  • Age>60; or Age<10；
  • Probiotics or prebiotics were taken before enrollment

Treatment and study plan

Primary outcomes

  1. Occurrence of GVHD

    Time frame: 90 days

    The occurrence time and degree of GVHD

Study contacts

Contact information is provided by the study sponsor or research team.

Depei Wu

CONTACT

[email protected]

+13812616208

xiaofei qi

CONTACT

[email protected]

+13812616208

Sponsors and collaborators

Lead sponsor

The First Affiliated Hospital of Soochow University

Other

Registry information

Official study title

Relationship Between the Utilization and Degradation Rate of "FODMAPs" by Intestinal Flora and "GVHD"

Important dates

Study start
2020
Primary completion
2026
Study completion
2026
First posted
Dec 9, 2020
Registry last updated
Dec 31, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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