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Completed

NCT Number: NCT07685691

Relationship Between Clinical Status and Nerve Conduction Test Findings in Patients With Unilateral Hemiplegia

Stroke-related hemiplegia may be accompanied by peripheral nerve conduction abnormalities, which may contribute to motor impairment and functional limitations. However, the frequency of these abnormalities and their relationship with clinical status have not been fully characterized. This single-center observational study aims to evaluate the frequency of peripheral nerve conduction abnormalities identified by nerve conduction studies in patients with unilateral hemiplegia and to examine their association with motor and functional clinical assessment scores. The findings may contribute to a better understanding of peripheral nerve involvement in stroke rehabilitation.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Başkent University Adana Dr. Turgut Noyan Application and Research Center

Adana, 01250, Turkey (Türkiye)

About this study

This is a single-center observational study designed to evaluate peripheral nerve conduction abnormalities in patients with unilateral hemiplegia following stroke. Participants undergo standardized nerve conduction studies together with routine clinical assessments, including validated measures of motor recovery and functional status. The study aims to describe the frequency of peripheral nerve conduction abnormalities within the study population and to examine their association with clinical assessment scores. The results may improve the understanding of peripheral nerve involvement in patients with hemiplegia and provide information that may be useful for rehabilitation practice.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults (≥18 years of age).
  • Unilateral hemiplegia secondary to ischemic or hemorrhagic stroke, or intracranial hemorrhage.
  • Ability to undergo standardized nerve conduction studies and clinical assessments.
  • Provision of written informed consent.

Exclusion criteria

  • Bilateral hemiplegia.
  • Hemiplegia secondary to benign or malignant intracranial tumors.
  • Upper or lower extremity fracture, amputation, skin lesions preventing electrophysiological testing, or diagnosed peripheral vascular disease.
  • Concomitant neurological disorders that may affect motor function or peripheral nerve conduction (e.g., Parkinson's disease, multiple sclerosis, encephalitis).
  • Contraindications to nerve conduction studies (e.g., cardiac pacemaker or inability to safely undergo the examination).
  • Inability to cooperate with or tolerate nerve conduction studies.

Treatment and study plan

Nerve Conduction Study

Diagnostic Test

Standardized motor and sensory nerve conduction studies were performed to evaluate peripheral nerve conduction abnormalities in patients with unilateral post-stroke hemiplegia. The test was used as a diagnostic assessment and was not part of a therapeutic intervention.

Other names: NCS

Primary outcomes

  1. Association Between Peripheral Nerve Conduction Abnormalities and Clinical Assessment Scores

    Time frame: Baseline

    To evaluate the association between peripheral nerve conduction abnormalities identified by standardized nerve conduction studies and motor and functional outcome measures in patients with unilateral hemiplegia secondary to ischemic or hemorrhagic stroke. The frequency of peripheral nerve conduction abnormalities within the study population will also be described.

Secondary outcomes

  1. Fugl-Meyer Assessment (FMA) Score (Upper and Lower Extremities)

    Time frame: Baseline

    Association between peripheral nerve conduction abnormalities and motor impairment assessed using the Fugl-Meyer Assessment.

  2. Functional Independence Measure (FIM) Score

    Time frame: Baseline

    Association between peripheral nerve conduction abnormalities and functional independence measured using the Functional Independence Measure.

  3. Timed Up and Go Test (TUG)

    Time frame: Baseline

    Association between peripheral nerve conduction abnormalities and mobility performance assessed using the Timed Up and Go test.

Sponsors and collaborators

Lead sponsor

Baskent University

Other

Registry information

Official study title

Prevalence of Peripheral Nerve Conduction Abnormalities and Their Association With Clinical Scores in Patients With Hemiplegia

Important dates

Study start
2024
Primary completion
2026
Study completion
2026
First posted
Jul 6, 2026
Registry last updated
Jul 14, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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