Relationship Between Circulating Tumor Stem Cells and the Clinical Pathology

The aim of this study is to establish a platform of detecting and sorting circulating tumor stem cells from peripheral blood in HCC patients; to investigate the relationship between circulating tumor stem cells and their effects on postoperative recurrence and metastasis, in order to provide a new therapeutic target for hepatocellular carcinoma treatment.

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Key information

Conditions

Cancer Stem Cells Adenocarcinoma Carcinoma Carcinoma, Hepatocellular Digestive System Diseases Digestive System Neoplasms Hepatocellular Carcinoma Liver Diseases Liver Neoplasms Neoplasm Metastasis Neoplasms Neoplasms by Histologic Type Neoplasms by Site Neoplasms, Glandular and Epithelial Neoplastic Processes Pathologic Processes Pathological Conditions, Signs and Symptoms Postoperative Recurrence and Metastasis

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Eastern hepatobilliary surgery hospital

Shanghai, Shanghai Municipality, 200438, China

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Male or female patients > 18 years and <=70 years of age;
No dysfunction in major organs; Blood routine, kidney function, cardiac function and lung function are basically normal.
Patients who can understand this trial and have signed information consent

Exclusion criteria

Reject to attend；
Impossible to come to our hospital for physical examination regularly;
Patients with other diseases which may affect the treatment mentioned

Treatment and study plan

Primary outcomes

the overall survival rate of each group

Time frame: 3 years

Sponsors and collaborators

Lead sponsor

Eastern Hepatobiliary Surgery Hospital

Other

Registry information

Official study title

A Prospective Randomized Trial on the Relationship Between Circulating Tumor Stem Cells and the Clinical Pathology

Important dates

Study start: 2012
Primary completion: 2014
Study completion: 2014
First posted: Apr 4, 2016
Registry last updated: Apr 4, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed