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Completed

NCT Number: NCT07468149

REHABOTICS: Physiotherapy for Hand Spasticity After Stroke Using Robotics and AR Serious Games

Rehabotics is a comprehensive rehabilitation system designed to deliver individualized upper-limb therapy for patients with motor impairments, particularly after stroke. Its core components include an exoskeletal robotic aid for assisted hand training and an interactive augmented reality platform for rehabilitation exercises and functional task practice. The system supports both treatment and assessment by enabling the monitoring of motor performance and patient progress through quantitative data. The overall aim of Rehabotics is to enhance the quality, intensity, and personalization of hand rehabilitation in clinical settings, with the potential to support remote care applications in the future.

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Key information

Conditions

Stroke Brain Diseases Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Nervous System Diseases Spasticity Post Stroke Upper Extremity Dysfunction Vascular Diseases

Age range

30 year–85 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Physioloft, Physiotherapy Center

Athens, Attica, 14562, Greece

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • stroke pathology,
  • Ashworth Scale ≤ 3,
  • 6 months maximum time since the incident

Exclusion criteria

  • Presence of neurological pathologies that affect hand motion (Parkinson's disease)
  • Musculoskeletal deficits that affect normal finger range of motion (e.g. finger fractures, joint stiffness/pain, arthritis that affect joint motion)
  • Ashworth Scale > 3,
  • Over 6 months since the incident

Treatment and study plan

Rehabotics Physiotherapy

Device

A supervised 5-week upper-limb rehabilitation program using the Rehabotics system, delivered in 3 sessions per week, with each session lasting 30 minutes. Each session combined two components: (1) task-oriented training through an augmented reality serious-games platform using markerless hand tracking with a standard RGB camera, and (2) assisted stretching of the affected finger flexor muscles using the Active Exoskeletal Aid. The AR component included grip-specific functional tasks designed to simulate activities of daily living. The exoskeletal component provided repetitive, therapist-adjustable finger stretching through servo motor-driven movement, with programmable parameters including extension speed, maximum extension angle, and return speed.

Primary outcomes

  1. Box and Block Test score measured by physiotherapists

    Time frame: Change from baseline to 5 weeks

    This outcome aims to explore the therapeutic potential of Rehabotics in stroke rehabilitation, demonstrating improved hand motor function through the integration of robotics and Augmented Reality games, measured by the Box and Block Test [BBT] score. The BBT consists of a wooden box divided into two compartments by a partition and includes 150 blocks. During the BBT administration, the patient is instructed to move as many blocks as possible, one by one, from one compartment to the other within 60 seconds. The higher the number of blocks moved indicate better manual dexterity.

  2. Ashworth Scale measured by physiotherapists

    Time frame: Change from baseline to 5 weeks

    This outcome aims to explore the therapeutic potential of Rehabotics in stroke rehabilitation, demonstrating improved hand motor function through the integration of robotics and Augmented Reality games, measured by Ashworth Scale [AS]. The AS is a key instrument for evaluating spasticity in individuals with upper extremity mobility challenges during rehabilitation. This assessment uses a scoring system from 0 to 4, where higher scores denote greater difficulty in finger movement, and lower scores indicate easier finger movement.

  3. AROM measured by physiotherapists using gioniometry

    Time frame: Change from baseline to 5 weeks

    This outcome aims to explore the therapeutic potential of Rehabotics in stroke rehabilitation by demonstrating improvements in active finger mobility through the integration of robotics and Augmented Reality games, measured by active range of motion (AROM). In this study, AROM was assessed as Total Active Motion (TAM), which is defined as the sum of active flexion at the metacarpophalangeal, proximal interphalangeal, and distal interphalangeal joints of the finger, minus any extension deficits at these joints. Measurements were obtained using a finger goniometer, and higher TAM values indicate better active finger movement and joint mobility.

Sponsors and collaborators

Lead sponsor

Pantelis Syringas

Other

Collaborators

  • Physioloft, Physiotherapy Center
  • University of Ioannina
  • University of Peloponnese

Registry information

Important dates

Study start
2023
Primary completion
2025
Study completion
2025
First posted
Mar 12, 2026
Registry last updated
Mar 12, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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