Rehabilitation of Taste and Smell Disorders Associated With Chemotherapy Using Aromatherapy

Changes in taste and smell can occur during chemotherapy treatment. These chemotherapy-related side effects can negatively impact patients' quality of life and diet.

The aim of this research is therefore to propose a solution to alleviate these taste and smell disorders. Based on the same principle as rehabilitation proposed for anosmia (loss of smell) related to COVID-19, we hypothesize that olfactory rehabilitation (using the sense of smell) through the odorous properties of essential oils could be effective for chemotherapy-related taste and smell alterations.

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Key information

Conditions

Cancer Neoplasms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Médipôle Hôpital Mututaliste

Villeurbanne, 69100, France

Location status: Recruiting

Location contact

laetitia paradisi

CONTACT

[email protected]

+33481655296

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

cancer treated with chemotherapy
patient with taste and/or smell disorders

Exclusion criteria

patient at the end of chemotherapy treatment

Treatment and study plan

experimental in day hospital

Other

multidisciplinary day hospital

taste and smell disorders questionnaire

Other

Answer to the home-made questionnaire at inclusion and at 6 months

Primary outcomes

difference in scores between 6 months and the inclusion at "taste and smell disorders" questionnaire

Time frame: 6 months

taste and smell disorders home-made questionnaire (score from 0 to 100)

Sponsors and collaborators

Lead sponsor

Médipôle Lyon-Villeurbanne

Other

Registry information

Acronym: AGORA

Important dates

Study start: 2022
Primary completion: 2026
Study completion: 2027
First posted: Jun 27, 2025
Registry last updated: Jun 27, 2025

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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