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OpenTrials
Completed

NCT Number: NCT05332379

Regional Hemodynamic Parameter Changes After Spinal Anesthesia

Spinal anesthesia is a regional anesthesia method used for surgical procedures generally involving the lower abdominal area, perineum, and lower extremities. Various tests are performed to evaluate the block level after spinal anesthesia, incluyding pinprick test, cold application, and motor examination. These tests are performed to check whether the pain, sympathetic and motor nerve fibers are affected, respectively, after the block; and good communication with the patient is important here. However, it is extremely difficult to evaluate these tests in pediatric, geriatric, mentally retarded or uncooperative patients.

Sympathectomy can be used as a criterion to evaluate the success of the block that occurs after the spinal anesthesia procedure. Sympathetic nerve fibers are the first to be affected by the block, and the success of the block can be evaluated with the revealed sympathectomy. Sympathectomy in the lower extremities after spinal block increases arterial blood flow. This increase in blood flow can be detected by the Pulsed Wave Doppler feature of USG.

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Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Marmara University School of Medicine

Istanbul, Pendik, 34899, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Elective surgery under spinal anesthesia
  • American Society of Anesthesiologists (ASA) I-II physical status

Exclusion criteria

  • Contraindication for spinal anesthesia
  • ASA physical status >II
  • Vasoactive drug usage

Treatment and study plan

Pulsed Wave Doppler USG examination

Diagnostic Test

Pulsed Wave Doppler USG examination of the posterior tibial artery on the left or right lower extremity will be performed before spinal anesthesia, at the 5th and 10th minutes after the spinal anesthesia. Blood flow velocities and vessel diameters will be measured.

Primary outcomes

  1. Arterial velocity changes

    Time frame: At the 5th and 10th minutes after the spinal anesthesia procedure

    Posterior tibial artery velocities (peak systolic, end-diastolic) and vessel diameters will be measured after the spinal anesthesia procedure.

Sponsors and collaborators

Lead sponsor

Marmara University

Other

Registry information

Official study title

Measurement of Regional Hemodynamic Parameters Before and After Spinal Anesthesia with Doppler USG

Important dates

Study start
2022
Primary completion
2023
Study completion
2023
First posted
Apr 18, 2022
Registry last updated
Dec 31, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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