Skip to main content
OpenTrials
Completed

NCT Number: NCT03066037

Regional-anaesthesiological Infiltration Techniques for the Management of Chronic Pain: a Retrospective Study

There is a significant debate whether local infiltration techniques may be a method to treat complicated chronic pain syndromes, e.g. refractory headache. Until now there is a lack of evidence regarding efficacy of this treatment especially in long term follow up. Similarly, indication and management are under debate. Aim of this trial is to analyse pain scores during first treatment with anaesthesiological infiltration series.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Chronic Pain Brain Diseases Central Nervous System Diseases Cluster Headache Cranial Nerve Diseases Facial Nerve Diseases Facial Neuralgia Headache Disorders Headache Disorders, Primary Mouth Diseases Nervous System Diseases Neuralgia Neuralgia, Postherpetic Neurologic Manifestations Neuromuscular Diseases Neuropathic Pain Pain Pathological Conditions, Signs and Symptoms Peripheral Nervous System Diseases Post Zoster Pain Post-Zoster Neuralgia Signs and Symptoms Stomatognathic Diseases Trigeminal Autonomic Cephalalgias Trigeminal Nerve Diseases Trigeminal Neuralgia

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Charité hospital

Berlin, State of Berlin, 13353, Germany

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients with chronic pain disease undergoing regional-anaesthesiological infiltration series

Exclusion criteria

  • pregnancy
  • patients in legal custody
  • age <18 years

Treatment and study plan

regional-anaesthesiological infiltration

Procedure

Patients with therapy refractory chronic pain are treated with local infiltration techniques using e.g. local anaesthetics, opioids or drug combinations. Targeted structures are e.g. Ganglion stellatum, Ganglion pterygopallatinum, Trigeminal nerve branches (V1-V3). Patients receive a context- sensitive number of blocks in a series of infiltrations depenting on their pain course.

Other names: block series

Primary outcomes

  1. NRS reduction during therapy

    Time frame: 2 weeks

    Reduction (relative and absolute) of pain during series of infiltrations comparing NRS scores before and after infiltrations

Secondary outcomes

  1. Number of blocks in a series

    Time frame: 4 weeks

    Number of blocks in a series to achieve the targeted NRS reduction

  2. Time till recurrent pain

    Time frame: 24 weeks

    Time until a new series of blocks is requested by the patient

  3. clinical course of pain

    Time frame: 2 weeks

    NRS development during series of infiltrations

  4. type of infiltration

    Time frame: 2 weeks

    location of infiltrations with medication used

  5. co-parameters of pain chronification

    Time frame: 2 weeks

    co-factors of pain like co-morbidity, duration of pain disease, psychological diseases and association with primary outcome

Sponsors and collaborators

Lead sponsor

Charite University, Berlin, Germany

Other

Registry information

Acronym: RetroBlock

Important dates

Study start
2009
Primary completion
2016
Study completion
2016
First posted
Feb 28, 2017
Registry last updated
Feb 28, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.