Practice of Sedation and Analgesia in Patients With Severe Brain Injury in China
NCT03975751
Agnosia, Brain Diseases
Beijing, Beijing Municipality, China
View Trial DetailsNCT Number: NCT05131633
Pain is a major problem in Intensive Care Unit (ICU). Adequate pain management not only means decreasing the pain intensity, but also improving the functionality and allowing the early mobilization that is a prerequisite for improving recovery and decreasing the risk of complications in ICU. The complex problems involved in pain, analgesic interventions, and outcome have been emphasized in several surveys over the past decades, but apparently with only small improvements, despite the existence of several guidelines for perioperative pain management.
Regional analgesia techniques (peripheral and neuraxial nerve blocks) have the potential to decrease the physiological stress response to trauma or surgery, reducing the possibility of surgical complications and improving the outcomes. Recent studies suggested that surgical and trauma ICU patients receive opioid-hypnotics continuous infusions to prevent pain and agitation that could increase the risk of posttraumatic stress disorder and chronic neuropathic pain symptoms, and chronic opioid use. Also they may reduce the total amount of opioid analgesics necessary to achieve adequate pain control and the development of potentially dangerous side effects. The use of the regional anesthesia technique in the ICU, however, can, in part, be limited by the presence of hemodynamic instability, bleeding diathesis, and by the fear of the performing procedures potentially associated with significant side effects in heavily sedated patients.
Although regional anesthesia emerges as a new and very interesting player for pain management in ICU, today very few data exists about the use of RA (including PNB and neuraxial nerves blocks) by the practicians in ICU/stepdown units. The main objective of this study is to assess the use of RA for pain management both initiates in the operative room for surgical patients then transferred in ICU/stepdown units and performs directly by the practicians in ICU/stepdown units, in several french units.
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Notify Me18 year and older
All sexes
Observational
CH, Aix-en-Provence, France
Taken together, previous data indicate that regional anesthesia emerges as a new and very interesting player for pain management in ICU.
Because very few data exist about the use of RA (including PNB and neuraxial nerves blocks) by the practicians in ICU we, therefore, design this multicentric professional practice evaluation to :
This study will have no effect on the management of the ICU/stepdown units patients.
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
○ All medical, surgical, and trauma patients hospitalized in the participating centers and receiving RA during the one-week study period.
Exclusion criteria
Time frame: During 1 week of the study
. Number (prevalence) of RA performed in ICU over 1 week.
Time frame: During 1 week of the study
.Number of RA performed in operative room and then transferred in ICU over a week.
. Prevalence of RA performed in the operative room and then transferred in ICU over a week
Time frame: During 1 week of the study
Nerves block or spinal anesthesia or epidural anesthesia
Time frame: During 1 week of the study
ICU or step-down unit or operating room
Time frame: During 1 week of the study
Resident or senior and intensivist or anesthesiologist
Time frame: During 1 week of the study
Name of local anesthetics used
Time frame: During 1 week of the study
Concentration in mg/ml
Time frame: During 1 week of the study
Analgesia or anesthesia or mobilization or nursing or weaning from mechanical ventilation
Time frame: During 1 week of the study
Type of needle
Time frame: During 1 week of the study
Use of sonography (yes / no)
Time frame: During 1 week of the study
Use of electrical nerve stimulator (yes / no)
Time frame: During 1 week of the study
Use of continuous catheter (yes / no)
Time frame: During 1 week of the study
Visual Analog Score for pain)
Time frame: During 1 week of the study
Sensitive and/or motor block
Time frame: During 1 week of the study
Type of contraindication
Time frame: During 1 week of the study
Type of complication
Time frame: During 1 week of the study
Type of reason
Time frame: During 1 week of the study
Duration in days
Time frame: Day 28 after the RA
Length in days
Time frame: Day 28 after the RA
Length in days
Time frame: Day 28 after the RA
Time frame: Day 28 after the RA
Death or alive
Time frame: Day 28 after the RA
Unit : days
University Hospital, Clermont-Ferrand
Other
Point-of-care Regional Anaesthesia in Intensive Care Unit. A Multicentric Professional Practice Evaluation
Acronym: Week'ALR
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