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NCT Number: NCT06815016

Reflexology and Mulligan Mobilization for Knee Osteoarthritis

to investigate the effect of adding Reflexlogy to mulligan mobilization and the conventional treatment for patients with Osteoarthritis knees

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Key information

Age range

40 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Cairo University

Cairo, Egypt

Location contact

Mariam O Grase, Lecturer of Physical Therapy

SUB_INVESTIGATOR

Noran a Elbehary, Professor of Physical Therapy

SUB_INVESTIGATOR

Rania a nassar, master

CONTACT

[email protected]

01010618797

About this study

Knee osteoarthritis (OA), also known as degenerative joint disease, is typically the result of wear and tear and progressive loss of articular cartilage. Treatment by reflexology stimulation increases blood flow to the associated organ or body part. On the other hand, the nerve impulse theory claims that reflexology stimulation boosts nervous connection to the conforming body parts. Regarding to the energy theory; organs and body parts are connected through electromagnetic fields and that these pathways are blocked in states of disease. Finally, lactic acid theory pointed that lactic acid accumulates on the soles of the feet in the form of crystals which promotes free circulation, so reduces regular flow .The effects of foot reflexology on improving physical complains of KOA. Therefore, this study was conducted to evaluate the effectiveness of reflexology foot massage on pain intensity and physical functional abilities among patients with Knee Osteoarthritis.

Mulligan's Mobilization with Movement (MWM) advocates therapist-applied accessory gliding force combined with active movement The goal of MWM is to achieve immediate pain relief possibly by regulation of the non-opioid pain sensory pathways and by correction of micro positional faults. These positional faults may result from changes in the shape of articular surfaces, cartilage thickness, fiber orientation in the capsule-ligamentous complex, and the direction of musculo-tendinous pull, causing altered mechanics in the osteoarthritic knees.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age greater than or equal to 40 years.
  • Body Mass Index ≤30 kg/m².
  • All participants have Calcium Deficiency
  • Osteoarthritis in mild and moderate stage not in the acute stage
  • The subjects were chosen from both genders

Exclusion criteria

  • Deep Vein Thrombosis
  • Fractures
  • Gangrena Patient
  • Osteopenic Patient
  • Lactating or pregnant women
  • Cancer
  • Neurological conditions.
  • Patients with injury including; (lesions, sprain, open wounds, foot ulcer and or burn of the lower extremities), hemorrhage, epilepsy, irregular heartbeat.
  • Vascular (Anticoagulant Therapy, Aortic Aneurysm)
  • Neurological Deficits (multilevel PIVD, Cervical Myelopathy)
  • Psychological Disorders.

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Treatment and study plan

Reflexology ,mulligan mobilization and conventional

Other

Reflexology is a systematic practice in which applying some pressure to any particular points on the feet and hands give impacts on the health of related parts of the body as (Knee reflex point, Pituitary reflex point, Entire spine, Liver reflex area, Thyroid reflex area ) Mulligan's Mobilization with Movement (MWM) apply accessory gliding force combined with active movement as (Lateral glide MWM for flexion / extension, Medial glide MWM for flexion / extension, Self-medial glide MWM for knee flexion/extension: home exercise)

reflexology and conventional

Other

Reflexology as (Knee reflex point, Pituitary reflex point, Entire spine, Liver reflex area, Thyroid reflex area ) and conventional methods as (Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound Therapy and exercises) treatment.

mulligan mobilization and conventional

Other

Mulligan mobilization as (Lateral glide MWM for flexion / extension, Medial glide MWM for flexion / extension, Self-medial glide MWM for knee flexion/extension: home exercise) and conventional methods as (Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound Therapy and exercises) treatment.

conventional treatment

Other

Conventional methods as (Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound Therapy and exercises) treatment.

Primary outcomes

  1. visual analogue scale

    Time frame: one month

    consists of a line, usually 10 cm long, ranging from no pain or discomfort (zero), to the worst pain that could possibly feel (10)

Secondary outcomes

  1. The Knee Injury and Osteoarthritis Outcome Score (KOOS)

    Time frame: one month

    The Knee injury and Osteoarthritis Outcome Score (KOOS) was developed as an extension of the WOMAC Osteoarthritis Index with the purpose of evaluating short-term and long-term symptoms and function in subjects with knee injury and osteoarthritis. The KOOS holds five separately scored subscales: Pain, other Symptoms, Function in daily living (ADL), Function in Sport and Recreation (Sport/Rec), and knee-related Quality of Life (QOL)

Other outcomes

  1. Kinovea

    Time frame: one month

    Kinovea is a free software that uses a virtual goniometer to measure joints for measure Flexion and Extension ROM of knee

Study contacts

Contact information is provided by the study sponsor or research team.

Rania a nassar, master

CONTACT

[email protected]

01010618797

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

The Effect of Adding Reflexology to Mulligan Mobilization for Patient With Knee Osteoarthritis

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Feb 7, 2025
Registry last updated
Feb 7, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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