Reference Values and Determinants of 6-minute Walk Test

6MWT will be used to evaluate the walking endurance. A 30-m indoor walkway will be used to conduct the test. The maximal distance covered at the end of the 6MWT will be recorded.

Patients will be classified by walking ability using FAC has six levels (0 to 5) that are classified according to the walking ability on the basis of the amount of physical support required, which are as follows: nonfunctional ambulatory(FAC 0); ambulatory, continuous manual contact to support body weight as well as to maintain balance or to assist coordination (FAC 1); ambulatory [level I], intermittent or continuous light touch to assist balance or coordination (FAC 2); ambulatory, dependent on supervision (FAC 3); ambulatory, independent, level surface only (FAC 4); and ambulatory, independent (FAC 5).

Upper extremity, hand and lower extremity motor recovery will be assessed using the Brunnstrom 6 sequential stages of motor recovery.

The Modified Ashworth Scale will be used to measure the severity of knee extensor, knee flexor and ankle plantar flexor spasticity. MAS scores will be added together to give a total MAS score. MAS is graded from 0 to 4. A score of 0 indicates no increase at all in muscle tone, and 4 indicates that the joint is rigid in flexion or extension.

The beck depression inventory (BDI) will be used to evaluate depression. The BDI consists of 21 questions about how the subject has been feeling in the last week. Each question has a set of at least four possible answers, ranging in intensity. A value of 0-3 is assigned for each answer, and the total score is compared with a key to determine the severity of depression .The standard cut off values are as follows: 0-9, minimal depression; 10-18, mild depression; 19-29, moderate depression; and 30-63, severe depression.

The mini-mental state examination will be used to describe mental and cognitive functions.

Star cancellation test will be used to describe neglect phenomenon.

Activities of daily living (ADL) will be assessed using the Barthel Index. The Barthel Index consists of 10 items that measure a person's daily functioning, specifically ADL and mobility. The items include feeding, bathing, grooming, dressing, toileting, transferring, walking on a level surface, going up and down stairs, and continence of bowel and bladder. A patient with a maximum score of 100 points is defined as continent, able to eat and dress independently, able to walk at least a block, and able to go up and down stairs.

Balance ability will be tested using the Berg Balance Scale (BBS), which includes 14 functional balance items, with scores ranging from 0 to 56 points; better balance is indicated by a higher score.