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Completed

NCT Number: NCT03784664

Reducing Pain in Emergency Department by Using Veinous Blood Gas Instead of Arterious Blood Gas

Blood gases are widely used in emergency and resuscitation services and are the key examination for exploring acid-base balance disorders (using pH, PaCO2 and HCO3 ) and gas exchange disorders (using PaO2 and PaCO2). This examination can be taken from both venous and arterial sample and its analysis depends on the type of blood sample. Currently, several studies have already shown the existence of a good correlation of pH and bicarbonates level between a venous and arterial sample. Thus, when this examination is prescribed for the purpose of highlighting and analyzing an acid-base disorder, venous blood gas is theoretically as efficient as arterial blood gas.

Due to the lack of evidence of benefit for the patient or the health care team of a venous blood gas rather than an arterial blood gas in the absence of suspicion of hypoxemia, arterial blood gas is currently the standard of care for the analysis of acid-base disorders. Indeed, among the university hospitals affiliated to the Paris Diderot University, the emergency departments carry out in their vast majority (4 of 5 E.D.) arterial blood gases. Demonstration of the superiority of veinous sample over arterial sample regarding pain could substantially modify current practices.

The investigator's main hypothesis is that, in the absence of suspicion of hypoxemia (normal oxygen saturation measured by plethysmography), the realization of a venous blood gas for the evaluation of the acid-base balance in the context of emergencies is less painful for patients, simpler for the health care team and provides sufficient biochemical information for the doctor in comparison with an arterial blood gas.

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Key information

Conditions

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Hôpital Beaujon, Clichy, France

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Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • necessity of blood gas analysis
  • age > 18 yo
  • SpO2>95% without supplemental oxygen
  • no altered level of consciousness: Glasgow Coma Scale=15

Exclusion criteria

  • Patient under guardianship or curatorship
  • confusional state or patient unable to understand the protocol
  • no social security

Treatment and study plan

Arterial blood gas

Diagnostic Test

arterial blood sample with puncture of the radial artery

Veinous blood gas

Diagnostic Test

veinous blood sample using peripheral venepuncture

Primary outcomes

  1. Pain score: Visual Analog Scale

    Time frame: Immediately after blood gas sample

    Pain is self-completed by the patient using a Visual Analog Scale. Visual Analog Scale for Pain is a continuous scale comprised of a line of 100 mm grading pain intensity anchored by "no pain" (score 0) and "worst imaginable pain" (score 100)

Secondary outcomes

  1. Number of attempts needed to obtain a blood gas sample

    Time frame: Immediately after blood gas sample

  2. Number of different operators needed to obtain a blood gas sample

    Time frame: Immediately after blood gas sample

  3. Ease of blood gas sampling procedure

    Time frame: Immediately after blood gas sample

    Ease of blood gas sampling procedure assessed by the operator using a four-levels likert scale ("easy","moderate","difficult" "very difficult")

  4. Failure of the blood gas sampling procedure

    Time frame: Immediately after blood gas sample

    Impossibility to obtain a blood gas sample

  5. Quality of information provided by the blood gas analysis: four levels likert scale

    Time frame: Immediately after having received blood gas analysis results

    Four-levels likert scale assessing doctor's satisfaction regarding the quality of gas information provided by the blood gas analysis ("very satisfied","satisfied","slightly satisfied","not satisfied"

Sponsors and collaborators

Lead sponsor

Assistance Publique - Hôpitaux de Paris

Other

Registry information

Acronym: VEINART

Important dates

Study start
2019
Primary completion
2019
Study completion
2019
First posted
Dec 24, 2018
Registry last updated
Jun 19, 2019

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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