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OpenTrials
Active, Not Recruiting

NCT Number: NCT05353478

Reducing Opioid Prescription After Kidney Stone Removal Surgery

The purpose of this study is to implement and assess a standard way of prescribing opioid pain medication following PCNL (a kidney stone removal surgery) to ensure patients are being discharged with an appropriate quantity of pain management medication.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Kidney Stone Calculi Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Kidney Calculi Kidney Diseases Male Urogenital Diseases Nephrolithiasis Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Urinary Calculi Urogenital Diseases Urolithiasis Urologic Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Mayo Clinic Rochester

Rochester, Minnesota, 55905, United States

About this study

Participants in this study will have their opioid pain medication prescription at discharge following PCNL (Percutaneous Nephrolithotomy, a kidney stone removal surgery) determined by an algorithm in addition to physician judgement. The goal of the algorithm is help physicians refine pain medication prescribing patterns for patients who have undergone PCNL in order to discharge patients with an appropriate quantity of pain management medication. The effectiveness of the algorithm will be assessed through participant surveys. Participants will complete a brief online survey on Days 3, 7, and 14 following hospital discharge and another phone-based survey 26-30 days after hospital discharge.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients undergoing percutaneous nephrolithotomy at Mayo Clinic Rochester.

Exclusion criteria

  • Unable or unwilling to provide informed consent.
  • Patients who require Intensive Care Unit admission after surgery.
  • Patients who have Clavien grade III or greater postoperative complications requiring additional intervention < 30 days after index procedure.

Treatment and study plan

Primary outcomes

  1. Unused opioid prescriptions

    Time frame: 30 days

    Number of unused opioids following recovery from percutaneous nephrolithotomy

Secondary outcomes

  1. Unfilled opioid prescriptions

    Time frame: 30 days

    Number of unfilled opioid prescriptions following recovery from percutaneous nephrolithotomy

  2. Opioid prescription refills

    Time frame: 30 days

    Number of opioid prescription refills following recovery from percutaneous nephrolithotomy

Sponsors and collaborators

Lead sponsor

Mayo Clinic

Other

Registry information

Official study title

Reducing Opioids After Percutaneous Stone Surgery

Important dates

Study start
2022
Primary completion
2024
Study completion
2026
First posted
Apr 29, 2022
Registry last updated
Aug 8, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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