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Completed

NCT Number: NCT05932329

Reducing Free Sugar Intakes: A Role for Sweet Taste II

This randomised controlled trial aims to assess the effects of three different types of dietary advice for reducing free sugar intakes, on intakes of free sugar, in a sample of the UK population.

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Key information

Conditions

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Bournemouth University

Bournemouth, US and Canada Only, BH12 5BB, United Kingdom

About this study

The primary objective of this randomised controlled trial is to assess the effects of three different types of dietary advice, for reducing total energy intakes (TEI) of free sugars. A total of 150 participants (age 18-65 years) consuming diets >5% total energy intake from dietary free sugars will be recruited from across the Dorset region. All participants will be asked to reduce their free sugar intake to <5% TEI, and to aid with this, they will be encouraged to reduce their intakes of specific foods identified as high in free sugars. Participants will also be advised to replace these foods with other foods dependent on their taste. Participants will be randomised to replace high sugar foods with: 1) foods that are low in sugars, but high in sweet taste; 2) food that are low in sugars, but high in other tastes; and 3) foods that are low in taste. The primary outcome will be changes in free sugar consumption from baseline to endpoint at week 4. Secondary outcomes will include change in: BMI; dietary profiles; sweetness preference; sweetness liking; food choices; low calorie sweetened food intakes and adherence levels at week 4.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • aged 18-65 years;
  • able to provide consent and complete all study materials;
  • consuming >5% of TEI from free sugars;
  • residing in the South of England, and able to attend Bournemouth University for testing.

Exclusion criteria

  • individuals who are pregnant or breastfeeding;
  • underweight (BMI <18.5);
  • have pre-existing clinical conditions such as diabetes mellitus, eating disorders, Crohn's disease and other illness's leading to participants receiving external nutritional advice and dietary restrictions;
  • have pre-existing medical conditions affecting swallow ability, taste and smell perception;
  • currently following a specific dietary programme (e.g.: Slimming World);
  • current smokers or have smoked within 3 months of the study start date.

Treatment and study plan

Dietary Advice

Behavioral

Dietary Advice provided

Primary outcomes

  1. Free sugar intakes

    Time frame: Baseline to week 4

    Percentage energy intake from free sugars, assessed using diet diaries

  2. Adherence

    Time frame: Baseline to week 4

    Adherence to the recommendations provided, assessed using diet diaries and self-reported adherence

Secondary outcomes

  1. Dietary Intakes

    Time frame: Baseline to week 4

    Nutrient composition and taste of dietary intakes, assessed using diet diaries

  2. Body weight

    Time frame: Baseline to week 4

    Body weight, in kg, assessed using researcher measurements

  3. BMI

    Time frame: Baseline to week 4

    BMI, in kg/m2, assessed using researcher measurements

  4. Waist circumference

    Time frame: Baseline to week 4

    Waist circumference, in cm, assessed using researcher measurements

  5. Body fat percentage

    Time frame: Baseline to week 4

    Body fat percentage, assessed using bioimpedence, as conducted by the researcher measurements

  6. Sweet food preferences

    Time frame: Baseline to week 4

    Preferences for various sweet foods/fluids, assessed using a taste test, where participants sample several sweet and non-sweet foods and rate them for pleasantness on a 100mm Visual Analogue Scale. Higher scores signify stronger preferences

  7. Sweet food perceptions

    Time frame: Baseline to week 4

    Perceptions of the strength of sweet taste for various sweet foods/fluids, assessed using a taste test, where participants sample several sweet and non-sweet foods and rate them for strength of taste on a 100mm Visual Analogue Scale. Higher scores signify stronger perceptions

  8. Sweet food intakes

    Time frame: Baseline to week 4

    Selection of sweet foods/fluids at a given meal, assessed where participants can consume freely from a meal composed of sweet and non-sweet foods, and proportion of sweet foods consumed is measured in terms of weight consumed

  9. Sweet food attitudes

    Time frame: Baseline to week 4

    Attitudes towards sugar, sweeteners, and sweet-tasting foods, assessed using a questionnaire, soon to be published. Higher scores denote stronger attitudes.

  10. Adverse events

    Time frame: Baseline to week 4

    Adverse events, assessed by self-report

  11. Eating-based attitudes

    Time frame: Baseline to week 4

    Attitudes towards eating, assessed using the Three Factor Eating Questionnaire (Karlsson J, et al. IJO 2000; 24: 1715-1725)

  12. Subjective Quality of Life

    Time frame: Baseline to week 4

    Quality of Life, measured using the SF-36 questionnaire (Ware et al, 1996), where Quality of Life is assessed out of 100, where a higher score demonstrates better quality of life

  13. Barriers and facilitators to success

    Time frame: Baseline to week 4

    An assessment of barriers and facilitators to success, assessed by self-report questionnaire

Sponsors and collaborators

Lead sponsor

Bournemouth University

Other

Registry information

Important dates

Study start
2023
Primary completion
2023
Study completion
2025
First posted
Jul 6, 2023
Registry last updated
Jun 25, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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