Reducing Fluids Intakes in Neonatal Intensive Care

During stay in the neonatal intensive care unit, newborns requires various treatments administered intravenously. The hidden fluid intake associated with these infusion can lead to fluid overlad, increasing the risk of complications.This study aims to describe the variation of hidden fluid intake associated with treatment infusion, develop a new care protocol for the administration of intravenous medication in the neonatal intensive care unit, and finally standardize care practices related to the infusion of medication to improve the safety and quality of care for newborns.

Completed

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Key information

Conditions

Neonatal Intensive Care Unit Female Urogenital Diseases and Pregnancy Complications Obstetric Labor Complications Obstetric Labor, Premature Pregnancy Complications Premature Birth Urogenital Diseases

Age range

1 day and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU Clermont-Ferrand

Clermont-Ferrand, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

newborns in neonatal intensive care
gestational age between 24 to 37 weeks of amenorrhoea
weight birth between 500g to 4500g

Exclusion criteria

newborn without intravenous divice

Treatment and study plan

hidden fluid intake

Procedure

comparaison of additionnel fluids intakes before and after practical modification

Primary outcomes

hidden fluid intake

Time frame: At Day 0, day 1, Day 7, Day 14, Day 19.

Volume in milliliters per kilogram of hidden intakes associated with continuous and intermittent drug treatments administered daily

Sponsors and collaborators

Lead sponsor

University Hospital, Clermont-Ferrand

Other

Registry information

Acronym: REFINI

Important dates

Study start: 2024
Primary completion: 2025
Study completion: 2025
First posted: Jul 20, 2026
Registry last updated: Jul 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed