Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT07477678

Red Light Therapy: a Potential Strategy to Reduce Sports Injury Risk?

This study investigates whether near-infrared light therapy can acutely improve ankle dorsiflexion mobility and hamstring flexibility, two factors associated with sports injury risk. Healthy adult students will complete three randomized conditions: a control session, a 10-minute cycling warm-up, and a 10-minute exposure to a red and near-infrared LED panel (MITO LIGHT®). Mobility and flexibility will be assessed before and after each condition using the Knee-to-Wall Test (KWT) and the Active Knee Extension Test (AKET). The study aims to determine whether photobiomodulation may serve as a potential strategy to reduce musculoskeletal injury risk.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Conditions

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Human Movement Laboratory, Escola Superior de Saúde da Universidade de Aveiro (ESSUA)

Aveiro, Aveiro District, 3810-193, Portugal

Location contact

Cláudio da Silva Ferreira, MSc Student

CONTACT

[email protected]

+351 913880653

Cláudio da Silva Ferreira, MSc Student

SUB_INVESTIGATOR

Mário Alexandre Gonçalves Lopes, PhD

CONTACT

[email protected]

About this study

This randomized crossover study examines the acute effects of near-infrared LED-based photobiomodulation on ankle dorsiflexion mobility and hamstring flexibility in healthy adults. Each participant will complete three sessions in randomized order: (1) control, (2) 10-minute cycling warm-up, and (3) 10-minute exposure to a red and near-infrared LED panel (MITO LIGHT®), emitting wavelengths range of 800-860 nm. The LED panel will be positioned at 15 cm distance at 100% intensity. Pre- and post-intervention assessments will include the Knee-to-Wall Test (KWT) and the Active Knee Extension Test (AKET). The study is conducted at the Human Movement Laboratory of the University of Aveiro and follows ethical approval from the CEIC-UA. Data will be anonymized and processed according to GDPR. The goal is to determine whether photobiomodulation may contribute to reducing sports injury risk by improving key biomechanical parameters.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Active and healthy university students
  • No current pain or injury in the lower limbs
  • Ability to perform the Knee-to-Wall Test (KWT) and Active Knee Extension Test (AKET)
  • Availability to attend all three sessions with at least 72 hours between assessments
  • Signed informed consent

Exclusion criteria

  • Use of photosensitizing medication currently or within the past 3 weeks (as collected in the medical questionnaire)
  • Recent musculoskeletal injury of the lower limbs or any sports-related injury with relevant downtime
  • Presence of pain, joint limitation, or any medical condition preventing safe performance of KWT or AKET

Treatment and study plan

Near-infrared photobiomodulation

Device

Exposure to a near-infrared LED panel emitting wavelengths range of 800-860 nm for 10 minutes at a distance of 15 cm and 100% intensity. Mobility and flexibility tests (KWT and AKET) are performed immediately before and after the exposure.

Cycling Warm-up

Other

10 minutes cycling warm-up on a stationary cycle ergometer at 55-75% of maximum heart rate, followed by mobility and flexibility assessments.

Primary outcomes

  1. Ankle dorsiflexion range of motion

    Time frame: Immediately before and immediately after each condition (control, cycling warm-up, and near-infrared photobiomodulation)

    Ankle dorsiflexion range of motion will be assessed using the weight-bearing lunge test (knee-to-wall test). The distance from the hallux to the wall (cm) will be measured with the knee touching the wall and the heel on the floor. Higher values indicate greater dorsiflexion mobility

Secondary outcomes

  1. Hamstring flexibility

    Time frame: Immediately before and immediately after each condition (control, cycling warm-up, and near-infrared photobiomodulation)

    Hamstring flexibility will be assessed using the active knee extension test (AKET). With the hip flexed to 90° in supine position, the participant will actively extend the knee, and the knee flexion angle (degrees) will be measured with a goniometer. Lower angles indicate greater hamstring flexibility.

Study contacts

Contact information is provided by the study sponsor or research team.

Cláudio da Silva Ferreira, MSc Student

CONTACT

[email protected]

+351 913880653

Mário Alexandre Gonçalves Lopes, PhD

CONTACT

[email protected]

Sponsors and collaborators

Lead sponsor

Cláudio da Silva Ferreira

Other

Registry information

Acronym: DIAERESIS

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Mar 17, 2026
Registry last updated
Mar 19, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.