Recruiting

NCT Number: NCT07206628

Real-world Study to Assess Adherence to IOP Lowering Therapy in Glaucoma Patients Using CONNECTDROP®

The goal of this real-life, national, multicentre, prospective clinical investigation is to describe the adherence rate over time in patients with glaucoma already treated with IOP-lowering eye drops using connected device CONNECTDROP®

The main questions it aims to answer are:

* The mean annual adherence rate, defined as the percentage of the prescribed doses taken by the patient * The adherence profile of each patient * The association between the adherence profile, the objective adherence data and the clinical data.

Participants will use the connected device CONNECTDROP® associated with the smartphone application on a daily basis.

Recruiting

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Key information

Conditions

Adherence to Glaucoma Therapy

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Besomed SRLS, Bari, Italy

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adult patient (≥ 18 years old), man or woman
Patient with a diagnosis of bilateral open angle glaucoma
Patients being prescribed with glaucoma eye drops in EASYGRIP® bottle for at least 6 weeks in monotherapy.
Patient willing to participate in the study
Patient who consents for data collection in the frame of the study

Exclusion criteria

Pregnant and/or lactating woman
Patient receiving another ocular treatment for a chronic condition (i.e. regular instillations for several months)
Protected patient: adult under guardianship, curatorship or other protection legal, deprived of liberty by judicial or administrative decision

Treatment and study plan

Primary outcomes

Adherence rate over time in patients with glaucoma already treated with IOP-lowering eye drops in EASYGRIP® bottle clipped with CONNECTDROP®

Time frame: From enrollment to the end of the study at 12 months

Assessment of the mean annual adherence rate, defined as the percentage of the prescribed doses actually taken by the patient (i.e. at least 2 instillations per day).

Study contacts

Contact information is provided by the study sponsor or research team.

Medical Affairs Director

CONTACT

[email protected]

+33 4 73 98 14 36

Sponsors and collaborators

Lead sponsor

Laboratoires Thea

Industry

Registry information

Official study title

Real-world Study to Assess Adherence to IOP Lowering Therapy in Glaucoma Patients Using CONNECTDROP®: the GRANITE Study (Glaucoma tReatment AdhereNce wIth connecTed dEvice in Italy)

Important dates

Study start: 2025
Primary completion: 2026
Study completion: 2027
First posted: Oct 3, 2025
Registry last updated: Nov 17, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.