Assiut university
Asyut, Egypt
NCT Number: NCT06922968
The study aims to evaluate the role of TRUS in improving the efficacy and safety of endoscopic enucleation of prostate and TURP.
Trial opening soon.
Get Notified50 year–80 year
Male
Interventional
Not applicable
Asyut, Egypt
Standard TURP is an established procedure for managing BPH but has limitations, including the risk of incomplete adenoma removal and complications such as bleeding. Research on transurethral enucleation techniques has demonstrated potential for improved outcomes, especially in larger prostates. However, challenges persist in achieving precise resection boundaries and minimizing intraoperative risks.
TRUS, widely utilized for prostate biopsy and volume assessment, has recently gained attention for its intraoperative applications. Studies show that real-time TRUS provides accurate imaging of prostate anatomy and resection planes, helping surgeons better differentiate adenomatous tissue from surrounding structures. This enhances surgical precision, reduces intraoperative bleeding, and minimizes residual tissue, leading to better outcomes in procedures like TURP and enucleation.
Current TURP and enucleation approaches depend heavily on endoscopic visual guidance, which, despite significant advancements, can lead to residual tissue, excessive bleeding, and prolonged recovery. While enucleation techniques have addressed some of these challenges, they remain less accessible due to high costs and steep learning curves, making them unsuitable for all healthcare settings.
Integrating TRUS into TURP or enucleation offers the potential to address these limitations by enhancing tissue differentiation and guiding precise resection. This study aims to evaluate the efficacy of TRUS in reducing complications, achieving complete tissue removal, and improving patient recovery outcomes, potentially paving the way for its routine adoption in BPH surgery.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
realtime TRUS guidance during the procedure (TURP and enucleation)
No TRUS guidance during the procedure (TURP and enucleation)
Time frame: At 12 weeks after the procedure
Intervention efficacy will be evaluated by comparing the Peak flow rate in ml/second.(measured by uroflowmetry) between the two groups
Contact information is provided by the study sponsor or research team.
Mahmoud Farouk Hassan, lecturer Of Urology
CONTACT
Mohamed mostafa Elsharkawy, assistant lecturer of Urology
CONTACT
Assiut University
Other
Standard Versus Transrectal Ultrasound (TRUS)-Guided Endoscopic Treatment of Benign Prostatic Hyperplasia: A Prospective Randomized Controlled Trial
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT07728071
BPH (Benign Prostatic Hyperplasia), Genital Diseases
Shatin, Hong Kong
View Trial DetailsNCT07538622
BPH (Benign Prostatic Hyperplasia), Genital Diseases
La Mesa, California, United States
View Trial DetailsNCT07710794
BPH (Benign Prostatic Hyperplasia), Genital Diseases
Jinan, Shangdong, China
View Trial DetailsNCT07623239
BPH (Benign Prostatic Hyperplasia), Genital Diseases
View Trial Details