REACH SVS Control Patient Cross-Over Study

Inclusion criteria

• Patient was enrolled in the REACH SVS Study control group and has completed their participation in the Study including the 12 month follow-up visit.
• Patient has received standard-of-care medical management and it has been stable for 6 weeks.
• Patient is willing to participate in a study, complete the required follow-up visits, and maintain consistent nutrition and exercise habits during the study period.

Exclusion criteria

• Patient is classified as ASA Class greater than P4 including presence of co-morbidity that could significantly increase the risk of a bronchoscopy procedure.
• Patient participated in a study of an investigational drug or device within the past 30 days prior to participation in this study.
• Patient has demonstrated unwillingness or inability to complete baseline data collection procedures.
• Patient has co-existing major medical disease that will limit evaluation, participation, or follow-up in the study.
• Patient is unable to provide informed consent.
• Patient is not an appropriate candidate for or is unable to tolerate, flexible bronchoscopy procedures.
• Patient has history of 4 or more hospitalizations for COPD exacerbation or respiratory infections in the past year and none have occurred in the prior 3 months.
• Patient has evidence of systemic disease or neoplasia expected to compromise survival during the 3-month study period
• Patient has demonstrated unwillingness or inability to complete screening or baseline data collection procedures.