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NCT Number: NCT06013189

Re-Adjustment of Sweep Gas Flow to the During the Rewarming Period of the Cardiopulmonary Bypass

The investigators designed this prospective observational study with the theory that alkalosis caused by decreased CO2 solubility due to temperature increase during the rewarming period of the Cardiopulmonary Bypass could be prevented by reducing the sweep gas flow during the rewarming period.

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Key information

Conditions

Optimal Sweep Gas Flow Acid-Base Imbalance Alkalosis Determination of Optimal Sweep Gas Flow for Different Phases of Cardiopulmonary Bypass Metabolic Diseases Nutritional and Metabolic Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Acıbadem Altunizade Hastanesi İstanbul

Istanbul, Altunizade, Turkey (Türkiye)

Location status: Recruiting

Location contact

Melis Tosun, MD

CONTACT

[email protected]

00905356694002

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients over 18 years of age
  • Elective CPB surgery

Exclusion criteria

  • Patients undergoing minimally invasive surgery
  • Patients undergoing robotic cardiac surgery,
  • Patients undergoing deep hypothermia,
  • Patients undergoing total circulatory arrest,
  • Patients whose FiO2 requirement is high that cannot be applied to target gas flow

Treatment and study plan

Gas Flow Adjustment

Other

Decreased gas flow causes PaCO2 to elevate and prevents alkalosis

Primary outcomes

  1. Arterial pH lever lower than 7.30

    Time frame: during the cardiopulmonary bypass and postoperative 24th hour

    maintaining physiological pH

Secondary outcomes

  1. rSO2 20% below initial value

    Time frame: during the cardiopulmonary bypass

    observing the rSO2 of brain during rewarming period

Study contacts

Contact information is provided by the study sponsor or research team.

Melis Tosun, MD

CONTACT

[email protected]

00905356694002

Sponsors and collaborators

Lead sponsor

Acıbadem Atunizade Hospital

Other

Registry information

Official study title

Re-Adjustment of Sweep Gas Flow to the During the Rewarming Period of the Cardiopulmonary Bypass to Prevent Alkalosis

Important dates

Study start
2023
Primary completion
2023
Study completion
2034
First posted
Aug 28, 2023
Registry last updated
Aug 28, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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