Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT04342013

RCT: The Effect of an Electronic Clinical Decision Support Application on Perioperative Medication Errors.

The purpose of this study is to assess the effect of a novel clinical decision support application on the rate of perioperative medication errors and preventable adverse medication events. The investigators hypothesize that the perioperative clinical decision support application will reduce the incidence of perioperative medication errors and adverse medication events compared to the standard of care.

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Conditions

Perioperative Medication Errors Perioperative Adverse Medication Events

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Anesthesia clinician (anesthesiologists, certified registered nurse anesthetists (CRNAs), student nurse anesthetists, fellows and residents) at Massachusetts General Hospital.

Exclusion criteria

  • Study staff

Treatment and study plan

Electronic Clinical Decision Support Application

Other

Robust, real-time medication-related clinical decision support application for use in the operating room. The application is fully integrated with existing clinical systems. It provides visual alerts for medication errors and adverse medication events at the point-of-care.

Primary outcomes

  1. Combined incidence of medication errors and adverse medication events in the perioperative setting

    Time frame: 6 months

    Number of medication errors and adverse medication events / number of medications administered

Secondary outcomes

  1. Incidence of medication errors the perioperative setting

    Time frame: 6 months

    Number of errors / number of medications administered

  2. Incidence of adverse medication events in the perioperative setting

    Time frame: 6 months

    Number of adverse medication events / number of medications administered

  3. Preventability of medication errors and adverse medication events

    Time frame: 6 months

    Four-point Likert scale for preventability: definitely preventable, probably preventable, probably not preventable, and definitely not preventability

  4. Severity of harm (or potential harm) associated with both medication errors and adverse medication events in the perioperative setting

    Time frame: 6 months

    Four-point Likert scale for severity:

    Fatal

    Life-threatening: The event has the potential to cause symptoms that if not treated would put the patient at risk of death.

    Serious: The event has the potential to cause symptoms that are associated with a serious level of harm that is not high enough to be life-threatening.

    Significant: The event has the potential to cause symptoms that while harmful to the patient pose little or no threat to the patient's function.

Study contacts

Contact information is provided by the study sponsor or research team.

Karen C Nanji, M.D., M.P.H.

CONTACT

[email protected]

(617) 724-8544

Sponsors and collaborators

Lead sponsor

Karen C. Nanji,M.D.,M.P.H.

Other

Registry information

Official study title

Impact of a Novel Electronic Clinical Decision Support Application on Perioperative Medication Errors and Adverse Medication Events: a Randomized Controlled Trial

Important dates

Study start
2027
Primary completion
2027
Study completion
2027
First posted
Apr 10, 2020
Registry last updated
Nov 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.