RCT of the Efficacy of the Ketogenic Diet in the Treatment of Epilepsy

A study of the efficacy and tolerability of two different ketogenic diets in children with drug resistant epilepsy; children resistant to at least two drugs randomised to reveive diet after baseline or after further 3m control period; in addition randomised to either MCT or classical ketogenic diet.

Completed

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Key information

Conditions

Epilepsy Brain Diseases Central Nervous System Diseases Nervous System Diseases

Age range

2 year–16 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Institute of Child Health, The Wolfson Centre

London, WC1N 1EH, United Kingdom

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Diagnosis of epilepsy for at least 2 years, resistant to at least two AEDs, at least 7 seizures/week

Treatment and study plan

Ketogenic diet

Dietary Supplement

Ketogenic diet

Primary outcomes

Change in seizure frequency

Time frame: 3 months

Secondary outcomes

Tolerability and assessment of ketosis and growth

Time frame: 3 months

Sponsors and collaborators

Lead sponsor

Institute of Child Health

Other

Registry information

Important dates

Study start: 2001
Study completion: 2006
First posted: Nov 29, 2007
Registry last updated: Nov 29, 2007

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed