RBM-007 in Treatment naïve Exudative Age-related Macular Degeneration

Inclusion criteria

• General Inclusion Criteria:

• Male or female patients, 50 years of age or older at baseline
• Patient has completed/signed an informed consent prior to any study-related procedures and is able to follow study instructions and likely to complete all required visits.

• Ocular Inclusion Criteria:
• Best Corrected Visual Acuity (BCVA) 5 - 73 ETDRS letters (20/800-20/40 Snellen equivalent), inclusive, in study eye
• Presence of choroidal neovascularization secondary to AMD
• Clear ocular media and adequate pupil dilation to permit good quality photographic imaging.

Exclusion criteria

• General Exclusion Criteria:

• Females who are pregnant, nursing, planning a pregnancy or who are of childbearing potential not using a reliable method of contraception.
• History or current evidence of hypersensitivity to any components of the study medication or fluorescein, as assessed by the investigator.
• Participation in any investigational drug or device study within 30 days prior to baseline
• History or current evidence of a medical condition that may, in the opinion of the investigator, preclude the safe administration of study medication or affect the results of the study.

• Ocular Exclusion Criteria:
• Active ocular or periocular infections, malignancy
• Aphakia
• History of pars plana vitrectomy in the study eye
• History of major ophthalmic surgery in the past 3 months in the study eye, or minor surgery in the past 30 days
• History of significant ocular disease other than exudative AMD that may confound results
• Uncontrolled glaucoma (defined as intraocular pressure >21mm Hg despite treatment with ocular hypotensive medications at baseline).