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Completed

NCT Number: NCT04550559

Rate of Spontaneous Stone Passage as Assessed Using Urinary Ultrasonography and Direct Urinary System Radiography

To evaluate the effect of masturbation on the spontaneous expulsion of distal ureteral stones 5-10 mm in size.

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Key information

About this study

This prospective randomized controlled study was performed between February 2018 and March 2020 after obtaining ethics committee approval.A total of 128 men with distal ureteral stones were randomly divided into 3 groups. All patients received standard medical therapy. Patients in group 1 (n=43) were instructed to masturbate at least 3-4 times a week, patients in group 2 (n=41) received tamsulosin 0.4 mg/day, and patients in group 3 (controls, n=44) received standard medical therapy alone. Rates of expulsion, need for analgesic, and ureterorenoscopic lithotripsy were compared between the groups.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age ≥18 years
  • presenting with renal colic and inguinal or lumbar pain
  • being diagnosed as having distal ureteral stones ≥5 mm and <10 mm in size

Exclusion criteria

  • age <18 years,
  • stones <5 mm or ≥10 mm in size,
  • intermediate (stones on the ureter-iliac artery cross)
  • proximal ureteral stones, multiple ureteral stones,
  • presence of urinary infection,
  • renal insufficiency,
  • high creatinine level,
  • severe hydroureteronephrosis,
  • history of open or endoscopic ureteral surgery,
  • vesicoureteral reflux,
  • neurogenic bladder,
  • erectile dysfunction,
  • inability or refusal to masturbate for any reason (such as religious beliefs)

Treatment and study plan

Endoscopic ureterolitotripsy

Procedure

Endoscopic ureterolithotripsy

Primary outcomes

  1. The rates of spontaneous distal ureteral stone (5-10 mm size) passage after 4 weeks masturbation

    Time frame: 4 weeks

    The rates of spontaneous distal ureteral stone (5-10 mm size) passage of patients who were instructed to masturbate at least 3-4 times a week (Group1); received tamsulosin 0.4 mg/day (Group2); received standard medical therapy alone Group3.

Sponsors and collaborators

Lead sponsor

Avrasya University

Other

Registry information

Official study title

Evaluation of the Effect of Masturbation on Distal Ureteral Stones: A Prospective Randomized Controlled Study

Important dates

Study start
2018
Primary completion
2020
Study completion
2020
First posted
Sep 16, 2020
Registry last updated
Sep 16, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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