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OpenTrials
Completed

NCT Number: NCT01655303

Rate Control in Atrial Fibrillation

Rate control in atrial fibrillation is a usual battle in emergency departments. Oral medications have a natural superiority to intravenous ones because they are easy-to-use and decrease the workload in busy emergency departments.

This study wants to find an effective oral medication for rate control in rapid ventricular response atrial fibrillation. Propranolol and Metoprolol, Diltiazem and Verapamil are compared in patients with a stable hemodynamic status.

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Key information

Conditions

Rapid Ventricular Response Atrial Fibrillation

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Rasoul-e-Akram Hospital

Tehran, Tehran Province, 14436151, Iran

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age more than 18 years old
  • Stability in hemodynamic

Exclusion criteria

  • Systolic blood pressure less than 90 mm Hg
  • Altered mental status attributable to rapid ventricular response atrial fibrillation
  • Acute pulmonary edema attributable to rapid ventricular response atrial fibrillation
  • Chest pain attributable to rapid ventricular response atrial fibrillation
  • Allergy to Propranolol or Metoprolol or Verapamil or Diltiazem
  • History of asthma

Treatment and study plan

Propranolol

Drug

Other names: Inderal

metoprolol

Drug

Other names: Metoral

Verapamil

Drug

Diltiazem

Drug

Primary outcomes

  1. Rate less than 100 per minute

    Time frame: In 1 hour

    Ventricular rate less than 100 per minute after 1 hour of per oral medication administration

Secondary outcomes

  1. Drugs adverse effects

    Time frame: 2 hours

    Drugs adverse effects seen in patients in 2 hours after per oral medication administration

  2. Unstability in hemodynamic

    Time frame: 2 hours

    Hemodynamic instability (systolic blood pressure less than 90 mmHg, loss of consciousness, pulmonary edema, chest pain)

Sponsors and collaborators

Lead sponsor

Tehran University of Medical Sciences

Other

Registry information

Official study title

Oral Propranolol, Diltiazem, Metoprolol and Verapamil in Atrial Fibrillation Rate Control in Patients With Stable Hemodynamic Status

Important dates

Study start
2011
Primary completion
2011
Study completion
2011
First posted
Aug 1, 2012
Registry last updated
Aug 1, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.