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Completed

NCT Number: NCT01779622

Rapid Versus Slow Ingestion of Mixed Meal: Influence on Islet and Incretin Hormone Secretion in Healthy Volunteers

To test the influence of rapid versus slow ingestion of a mixed meal on insulin and incretin hormone secretion in healthy volunteers

Completed

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Key information

Conditions

Healthy Volunteers Recruited From the General Population Glucose Metabolism Disorders Hyperinsulinism Insulin Resistance Metabolic Diseases Nutritional and Metabolic Diseases

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Department of Clinical Sciences, Lund University

Lund, 22184, Sweden

About this study

A mixed meal (524 kcal) is ingested rapidly (within 5 min) or slowly (10-15 min) and changes in insulin, glucagon, GIP and GLP-1 levels are followed for subsequent 300 min

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy subjects

Exclusion criteria

  • Diabetes Liver disease Kidney disease Thyroid disease

Treatment and study plan

Mixed meal

Other

Ingestion of mixed meal

Primary outcomes

  1. Area under the curve for insulin

    Time frame: 300 min

Secondary outcomes

  1. Area under the curve for glucose-dependent insuinotropic polypeptide

    Time frame: 300 min

  2. Area under the curve for glucagon-like peptide-1

    Time frame: 300 min

Other outcomes

  1. Area under the curve for glucagon

    Time frame: 300 min

Sponsors and collaborators

Lead sponsor

Lund University

Other

Registry information

Official study title

Rapid Versus Slow Ingestion of Mixed Meal: Influence on Islet and Incretin

Important dates

Study start
2013
Primary completion
2014
Study completion
2014
First posted
Jan 30, 2013
Registry last updated
Sep 30, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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