Rapid Diagnosis of Severe Respiratory Tract Infectious Diseases and Screening of Biomarkers for Stratified Diagnosis

Methods: The relationship between relevant biomarkers and stratified diagnosis was analyzed by collecting laboratory and etiological examinations of patients with severe pneumonia.

Inclusion criteria

• Meets the diagnostic criteria for severe pneumonia；
• Age≥18 years old and < 80 years old；
• Willing to sign informed consent for the course of the study；

Exclusion criteria

• Patients with intracranial hypertension, acute coronary syndrome, pleural fistula, pneumothorax, or subcutaneous emphysema;
• Pregnant and lactating patients;
• Severely hemodynamically unstable (an increase in vasopressors by more than 30% in the first 6 hours, or norepinephrine >0.5mg/kg/min);
• Those who do not consent to participate in this study；