Rapid Cool: Heat Stroke Treatment

Inclusion criteria

• Adult participant (18 - 39 years old)
• Body mass index (BMI) 18 - 30 kg/m2
• At least moderate intensity aerobic exercise ≥60 min per week
• Participant is able and willing to follow study procedures

Exclusion criteria

• History of cardiovascular, neurological, metabolic, pulmonary, renal, gastrointestinal, or autoimmune disease
• Taking prescription medication (with exception of psychiatric medication)
• If taking a psychiatric medication, the dosage has changed within the month prior to first study visit
• Cannot abstain from taking over-the-counter medications or supplements for 24 hours before study visits (with exception of vitamins)
• Resting systolic blood pressure ≥130 mmHg and/or diastolic blood pressure ≥90 mmHg
• Resting heart rate of ≥100 beats per minute
• Regular smoker of cigarettes or has regularly smoked in the past year
• Musculoskeletal injury/condition that negatively impacts the protocol
• History of heat illness that resulted in a visit to a medical center in the past 2 years
• Has donated blood or plasma in the past 3 months
• Has taken antibiotics or corticosteroids within 4 weeks of enrollment
• Has a medical implant device such as a pacemaker, patient monitoring system, or metallic implant
• Has a full or partially amputated limb
• Pregnant or breastfeeding
• Study physician or PI discretion based on any other medical condition or medication