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Recruiting

NCT Number: NCT06335251

Radiotherapy Treatments for Neoplasms of the Limbs

In this observational study patients treated at European Institute of Oncology with radiotherapy to limbs will be included

Recruiting

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

European Institute of Oncology

Milan, Italy

Location status: Recruiting

Location contact

Barbara Alicja Jereczek

CONTACT

About this study

Approximately 60% of patients with neoplasms receive radiotherapy as part of their oncological treatment. Various primary tumors as well as metastases of various origins can be localized in the upper or lower limbs. Patients with such neoplastic localizations will therefore receive radiotherapy treatment possibly associated with other systemic or surgical treatments.

Treatment choice is usually established following multidisciplinary discussions, based on disease characteristics and stage, concurrent pathologies and pharmacological treatments, patient preferences, and functional aspects.

Data collection related to radiotherapy plays a crucial role in understanding various clinical aspects of the treatment itself. The availability of data from an increasing number of patients will allow the identification of clinical situations or technical parameters of radiotherapy correlated with treatment tolerance and effectiveness, aiming to identify the best treatment for these oncological pathologies.

This project aims to collect data related to radiotherapy treatments for primary or secondary neoplasms localized in the upper or lower limbs for scientific dissemination with the goal of establishing the basis for evaluating achieved results over time, and deriving from these elements useful for guiding the most effective treatment strategies and appropriate operational protocols.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients treated with radiotherapy for curative, palliative, neo-adjuvant, and adjuvant purposes in the upper and lower limbs for:

Primary bone tumors, Primary soft tissue tumors, Primary tumors of the cardio-circulatory system, Primary tumors of the lymphatic system, Primary tumors of the nervous system and skin, Secondary metastases from various origins localized in that district.

  • Signed informed consent

Exclusion criteria

  • Radiotherapy in districts other than limbs.

Treatment and study plan

Primary outcomes

  1. Overall survival

    Time frame: 5 years

    Number of patients death

  2. Disease free survival

    Time frame: 5 years

    Number of oncological event (local recurrence, distant metastasis, other primary tumor)

Study contacts

Contact information is provided by the study sponsor or research team.

Barbara Alicja Jereczek

CONTACT

[email protected]

+39 02 57489326

Sponsors and collaborators

Lead sponsor

European Institute of Oncology

Other

Registry information

Important dates

Study start
2018
Primary completion
2025
Study completion
2025
First posted
Mar 28, 2024
Registry last updated
Aug 28, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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