Radiological and Surgical Analysis of Frontal Recess Variations in Endoscopic Sinus Surgery

Introduction

The frontal recess is a narrow and anatomically variable region that forms the frontal sinus drainage pathway. Variations in its anatomy, particularly those related to the agger nasi cell and other frontal recess cells, can impair frontal sinus drainage and contribute to the development of frontal sinus disease. High-resolution computed tomography and endoscopic evaluation are essential for identifying these variations and planning endoscopic sinus surgery. A thorough understanding of frontal recess anatomy is crucial for achieving adequate frontal sinus drainage, improving surgical outcomes, and minimizing complications due to the close proximity of the orbit and skull base.

The Study aim to evaluate the anatomical variations of the frontal recess using radiological and surgical assessment and determine their significance in the management of frontal sinus disorders during endoscopic sinus surgery.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Frontal Sinusitis Endoscopic Sinus Surgery Frontal Sinus Recess Infections Nose Diseases Otorhinolaryngologic Diseases Paranasal Sinus Diseases Respiratory Tract Diseases Respiratory Tract Infections Sinusitis

Age range

20 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Alazhar university Hopital in Assiut

Asyut, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age : (20 -60 years old ).
Sex: both males and females.
Patients were selected from the otorhinolaryngology outpatient clinic of Al-Azhar University Hospital in Assiut in a consecutive manner.
All patients were generally well and fit for surgery.

Exclusion criteria

Patients with massive inflammatory disease of specific in
infections (e.g., rhinoscleroma).
Malignancy.
Severe nasal trauma.
Foreign body.
Previous nasal surgery.
Atrophic diseases or systemic diseases and patients not fit for surgery.

Treatment and study plan

endosocpic sinus surgery

Procedure

Endoscopic sinus surgery to drain the frontal sinus and detect how easy it will be during surgery and its relation to anatomical variations

Primary outcomes

Size distribution of Agar nasi cells

Time frame: Baseline

Distribution of different sizes of agar nasi cells among the participants: small, medium, and large
Prevalence of aggar nasi cell

Time frame: Baseline

The frequency of presence of aggar nasi cells on one side, bilateral, or absent

Sponsors and collaborators

Lead sponsor

Al-Azhar University

Other

Registry information

Official study title

A Radiological and Surgical Analysis of Anatomical Variations of Frontal Sinus Recess and Its Surgical Importance in the Management of Frontal Sinus Disorders During Endoscopic Sinus Surgery

Important dates

Study start: 2025
Primary completion: 2026
Study completion: 2026
First posted: Aug 6, 2026
Registry last updated: Aug 6, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Not Yet Recruiting