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Completed

NCT Number: NCT06765148

Radiodiagnostic Properties of Maxillary Antroliths

Background: To evaluate the frequency and radiodiagnostic characteristics of maxillary antroliths using cone beam computed tomography.

Materials and Methods: A review of 1166 patients aged 11-85 years was conducted to assess the frequency of maxillary antroliths, considering sex, age, and location. The relationship between antroliths and sex, location, dental treatment status, and sinus inflammation was evaluated. The shape, size, and volume of the antroliths were also analyzed. Significance was set at p=0.05 for statistical analysis.

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Key information

Age range

11 year–85 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Recep Tayyip Erdogan University Training and Research Hospital

Rize, 53100, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • DPR and CBCT and also had a maximum of 3 months
  • Image quality was sufficient
  • No artifacts CBCT images

Exclusion criteria

  • Tomographic images that contained pathologies such as cysts/tumors in the
  • Insufficient diagnostic quality
  • History of maxillofacial trauma or surgery, any syndrome/bone-related disease/metabolic disease
  • Insufficient diagnostic quality or patient position-related artifacts

Treatment and study plan

Retrospective radiologic study

Other

Retrospective radiologic study

Primary outcomes

  1. Antrolith descriptive analysis

    Time frame: for three days from the beginning of the study

    CBCT images were examined in axial, sagittal, and coronal slices to investigate the presence of antroliths. The age and sex information of the detected cases were recorded.

  2. Antrolith localization and relationship the dental status evaluation

    Time frame: for three days from the beginning of the study

    Each sinus cavity exhibiting antroliths was evaluated for distribution and location as follows: (1) unilateral or bilateral, (2) single or multiple, (3) tooth extraction/root canal treatment/residual root fragment/implant/periodontal disease and/or periapical lesion (any dental cause of sinus inflammation), (4) premolar or molar region, and (5) sinus floor, lateral wall, or medial wall.

  3. Antrolith and mucosal thickness classification

    Time frame: for three days from the beginning of the study

    the detected antroliths were categorized according to the classification of Cho et al. In this classification made according to the sizes of antroliths, Punctate = ≤3 mm in both height and width, Linear = ≤3 mm and more than treble in width, and Amorphous = >3 mm in both width and height.

    Additionally, the locations of the openings of the maxillary sinus ostiums were evaluated, and mucosal thickening, if any, was measured. Mucosal thickness measurements were made on coronal slices using NewTom's NNT viewer measuring tool. Similar to Chen et al., the sinus membrane thickness was measured perpendicular to the bone wall, from the maximum thickest region. Similar to Chen et al.'s classification of sinus membrane thickness measurements, which used Block and Dostoury's classification, the mucosal thickness was classified into three subgroups: membrane thicknesses <2 mm, 2-5 mm, and >5 mm. Also, similar to the article by Cho et al., the degree of inflammation in the maxillary sinus was

  4. Antrolith volume measurement

    Time frame: for three days from the beginning of the study

    3D reconstruction and volume measurements of antroliths were performed using the ITK SNAP software (free software under the GNU General Public License developed by the National Institutes of Health, the US National Institute of Biomedical Imaging and Bioenergy needs, the US National Library of Medicine, the Universities of Pennsylvania and North Carolina, and an independent group of developers).

  5. Different images evaluation for antrolit

    Time frame: for three days from the beginning of the study

    In addition, the visibility of antroliths detected on CBCT was also evaluated using panoramic radiographs taken from the patient (Fig 2). The detectability of antroliths in DPRs was evaluated by observers as detectable, suspicious, and undetectable.

Sponsors and collaborators

Lead sponsor

Recep Tayyip Erdogan University Training and Research Hospital

Other

Registry information

Official study title

Radiodiagnostic Properties of Maxillary Antroliths: a Retrospective Cone Beam Computed Tomography Study

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Jan 9, 2025
Registry last updated
Jan 9, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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