Skip to main content
OpenTrials
Completed

NCT Number: NCT02696447

Radiation Impact on Thromboembolic Events

The aim of the present study is to determine the frequency and to identify main risk factors for venous thromboembolism of venous thromboembolic complications in a population of cancer patients treated with a curative intent by ionizing radiation.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Malignant Neoplasm Cardiovascular Diseases Embolism and Thrombosis Neoplasms Thrombosis Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CH de Roanne, Roanne, France

Loading trial locations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patient with a solid cancer (all locations) treated with radiation therapy and / or brachytherapy as curative intent
  • to be 18

Exclusion criteria

  • Patient with metastatic cancer,
  • Patients whose follow-up at 6 months is not possible
  • Patient receiving an anti-coagulative medication (curative doses)
  • Pregnant or breastfeeding women,
  • Person under protection of justice or unable to give consent

Treatment and study plan

Biomarkers assays

Biological

D-Dimer assays, C-reactive protein, blood platelets assays

Primary outcomes

  1. Venous Thromboembolism event

    Time frame: 6 months

    All venous thromboembolism, whether symptomatic or discovered incidentally, objectified (CT angiography, lung scintigraphy, venous Doppler) between J1 of radiation treatment, up to 6 months following discontinuation of radiation treatment

Secondary outcomes

  1. Dosage of D-dimer

    Time frame: 6 months

  2. C-reactive protein

    Time frame: 6 months

  3. Complete blood count

    Time frame: 6 months

  4. Time of occurrence of VTE

    Time frame: 6 months

    Time of occurrence of VTE

  5. Symptomatic VTE

    Time frame: 6 months

    Symptomatic VTE.

Sponsors and collaborators

Lead sponsor

Institut de Cancérologie de la Loire

Other

Collaborators

  • CH Roanne
  • Centre Hospitalier Universitaire de Saint Etienne

Registry information

Official study title

Radiation Therapy and Venous Thromboembolic Events

Acronym: RIT

Important dates

Study start
2016
Primary completion
2018
Study completion
2019
First posted
Mar 2, 2016
Registry last updated
Jan 29, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.