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NCT Number: NCT07033117

RaDIANT Health Systems Intervention

The overarching goal of the proposed study is to determine whether the addition of structural interventions at the health system level targeting upstream barriers in the transplant process will improve access to transplant evaluation start.

Recruiting

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Key information

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Emory Transplant Center, Atlanta, Georgia, United States

Loading trial locations.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Five large transplant centers (Emory Transplant Center and Piedmont Transplant Center in Atlanta, GA; Medical University of SC; Duke University in Durham, NC; and Indiana University in Indianapolis, IN) ~800 referring dialysis center referring to these transplant centers

Exclusion criteria

  • Individuals referred, initiating evaluation, and waitlisted at non-participating start centers

Treatment and study plan

Performance Feedback Reports on Referral and Evaluation Closures

Other

Performance feedback reports will reflect each transplant center's performance related to kidney transplant evaluation initiation and referral closure. These reports aim to help centers understand common reasons why patients do not initiate the evaluation process or failed to proceed beyond the evaluation process, and to identify patterns in referral and evaluation closure practices. Reports will be individualized and distributed quarterly to the transplant center champion by the intervention lead.

Dialysis Facility Awareness Campaign

Other

As part of the intervention, dialysis centers will participate in an Awareness Campaign designed to educate staff about transplant center quality improvement efforts and how they may be contacted as part of the project. This campaign may include brief webinars or informative documents distributed via platforms such as IPRO Learn.

Patient Contact via Preferred Method

Other

Transplant centers will contact patients using their preferred method of communication.

Phone Call to Dialysis Facility During the Patient's Dialysis Session

Other

Facilities will enhance their patient communication procedures by making a phone call to the dialysis facility during the patient's dialysis session if the patient has not responded to initial outreach attempts. This additional step increases the likelihood of reaching the patient during a time when they are accessible and can engage in scheduling or follow-up.

Phone Call to Provider

Other

Transplant centers will enhance their outreach procedures by making a phone call to the referring provider (e.g., nephrologist, medical assistant) or another provider involved in the patient's care (e.g., primary care provider) in the event of self-referral if the patient has not responded to initial outreach attempts or "no-shows" an initial evaluation appointment. This additional step ensures that the referring provider is informed of the patient's progress and can assist in re-engagement or decision-making prior to referral closure.

Transplant Referral Communication Platforms or Email to Communicate Patient Status and No-Show

Other

Transplant center staff will utilize transplant referral communication platforms and/or email to communicate updates to dialysis staff regarding patient status (e.g., unable to contact the patient or no-show) before referral closure.

Audit and Tracking of Patient Contact Attempts Prior to Referral Closure

Other

Transplant center staff will continue internally tracking the frequency that a patient is contacted before closure and the date of closure, in alignment with center standard practice. This intervention introduces an audit process to be conducted before closure to ensure that all contact attempts (including one or more attempts to contact the patient directly, one or more phone calls to the alternate preferred contact, or one or more attempted contacts to the dialysis unit to connect with the patient), in alignment with center communication procedures, are appropriately executed.

Primary outcomes

  1. Change in transplant evaluation start within 6 months of transplant referral

    Time frame: Baseline, Post Intervention (Up to one year)

    The difference in the proportion of patients starting transplant evaluation within 6 months of being referred from baseline to up to one-year post-intervention

Secondary outcomes

  1. Change in transplant waitlisting

    Time frame: Baseline, Post Intervention (Up to one year)

    The difference in the proportion of patients waitlisted from baseline and up to one-year post-intervention

  2. Change in transplant receipt among those who were waitlisted

    Time frame: Baseline, Post Intervention (Up to one year)

    The difference in the proportion of patients who received a transplant among those who were waitlisted from baseline and up to one-year post-intervention

Sponsors and collaborators

Lead sponsor

Indiana University

Other

Collaborators

  • Duke University
  • Emory Healthcare
  • Indiana University Health
  • Medical University of South Carolina
  • National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
  • Piedmont Healthcare

Registry information

Official study title

The RaDIANT Health Systems Intervention for Improving Access to Kidney Transplantation

Important dates

Study start
2025
Primary completion
2027
Study completion
2027
First posted
Jun 24, 2025
Registry last updated
May 26, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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