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NCT Number: NCT05160259

Radial Visualization of the Foramen Arcuale Atlantis

Hemodynamics in the craniovertebral zone is often disturbed under the influence of a spondylogenic factor A complication of such changes can be from a slight decrease in cerebral circulation to ischemic changes in the vascular bed The patients underwent complex radiation diagnostics of the craniovertebral region of patients with verified Kimmerle's anomaly (N = 62) All examined patients underwent multispiral computed tomography (CT), ultrasound Doppler and transcranial Doppler (TCD) of the vertebral arteries (VA) Studies of the developmental variant of the first cervical vertebra with the presence of a bony bridge have shown that Kimmerle's anomaly can occur in all age groups

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Sex eligibility

All sexes

Study type

Observational

Primary location

Samarkand State Medical Institute

Samarkand, 140100, Uzbekistan

About this study

The vaulted hole was found in all age groups (more in young and middle age) The detection rate was within 16 3% of cases, that is, it occurs in every 5-6 people According to TCD data, Kimmerle's anomaly affects blood flow and was most often detected on both sides of the atlas In the unilateral variant, the anomaly was noted only on the left side It was found that the main structural change in the cerebral vascular bed, according to ultrasound diagnostics, is a change in the straightness of the vertebral arteries in the transverse processes of the cervical spine, including the atlas It should also be borne in mind that due to the complexity and mobility of the structure, patients with dysfunction of the craniovertebral zone receive therapy from doctors of various profiles, which requires a comprehensive diagnosis of this problem

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients manifested themselves in the form of dizziness, various types of headache, mainly localized in the occipital region, nausea or flashing of flies before the eyes, in the rest - only cervicalgia

Exclusion criteria

  • acute stroke, brain tumor

Treatment and study plan

Radial visualization of the foramen arcuale atlantis

Radiation

In patients with diagnosed Kimmerle's anomaly, using transcranial Doppler sonography to determine the degree of changes in blood flow in the vertebral arteries

Primary outcomes

  1. Radial visualization of the foramen arcuale atlantis

    Time frame: up to 36 months

    acute stroke, brain tumor

Sponsors and collaborators

Lead sponsor

Samarkand State Medical Institute

Other

Registry information

Important dates

Study start
2020
Primary completion
2026
Study completion
2026
First posted
Dec 16, 2021
Registry last updated
Dec 16, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.