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Active, Not Recruiting

NCT Number: NCT04409236

Quit2Heal Smartphone App in Helping Cancer Patients Quit Smoking

This phase III trial compares the Quit2Heal smoking cessation smartphone application (app) to the QuitGuide app in helping cancer patients quit smoking. Both apps provide tools to cope with urges to smoke, step-by-step guides for quitting smoking, help in planning for quitting and staying tobacco-free, and scientifically-based recommendations for how to select medications that aid in smoking cessation.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Primary location

Fred Hutch/University of Washington Cancer Consortium

Seattle, Washington, 98109, United States

About this study

OUTLINE: Patients are randomized to 1 of 2 arms.

ARM I: Patients receive the Quit2Heal app and are encouraged to use it frequently. During the entire 12-month follow-up period, the app will remain fully available anytime study participants wish to use it.

ARM II: Patients receive the QuitGuide app and are encouraged to use it frequently. During the entire 12-month follow-up period, the app will remain fully available anytime study participants wish to use it.

After randomization, patients are followed up at 3, 6, and 12 months.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 18 or older
  • Diagnosed with cancer within the past 24 months or currently receiving or planning to receive cancer treatment in the next 3 months
  • Smoked a cigarette (even a puff) in the past 30 days
  • Interested in learning skills to quit smoking
  • Willing to be randomly assigned to either smartphone application
  • Live in the United States and will remain in the United States (US) for the next 12 months
  • Have at least daily access to their own smartphone
  • Know how to download a smartphone application
  • Be willing and able to read English
  • Not currently (i.e., within past 30 days) using other smoking cessation interventions
  • Have never participated in our prior research trials
  • Have never used the National Cancer Institute (NCI)'s QuitGuide app
  • Being willing to complete a follow-up survey at 3, 6, and 12 months post-randomization
  • Providing email, phone number(s), and mailing address

Exclusion criteria

  • Currently (i.e., within past 30 days) using other smoking cessation interventions
  • Has participated in our prior research trials
  • Has used the NCI's QuitGuide app
  • Not willing to complete a follow-up survey at 3, 6, and 12 months post-randomization
  • Not providing email, phone number(s), and mailing address

Treatment and study plan

Quit2Heal

Behavioral

Use Quit2Heal app

Other names: Quit2Heal App, Quit2Heal Smartphone App, Quit2Heal Smartphone Application

QuitGuide

Behavioral

Use QuitGuide app

Other names: QuitGuide App, QuitGuide Smartphone App, QuitGuide Smartphone Application

Survey Administration

Other

Ancillary studies

Primary outcomes

  1. Number of participants with 30-day cigarette smoking cessation at 12 months.

    Time frame: At 12 months after randomization

    No smoking at all in the past 30 or more days.

Secondary outcomes

  1. Number of participants with 30-day cigarette smoking cessation at 3 months.

    Time frame: At 3 months after randomization

    No smoking at all in the past 30 or more days.

  2. Number of participants with 30-day cigarette smoking cessation at 6 months.

    Time frame: At 6 months after randomization

    No smoking at all in the past 30 or more days.

Sponsors and collaborators

Lead sponsor

Fred Hutchinson Cancer Center

Other

Collaborators

  • American Cancer Society, Inc.
  • Memorial Sloan Kettering Cancer Center
  • National Cancer Institute (NCI)

Registry information

Official study title

Randomized Trial of a Smartphone Application to Help Cancer Patients Stop Smoking (Quit2Heal)

Important dates

Study start
2021
Primary completion
2025
Study completion
2026
First posted
Jun 1, 2020
Registry last updated
Sep 17, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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