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Completed

NCT Number: NCT03081403

Quantitative Sensory Testing in Subjects With Sensitive Skin or Not

Sensitive skin is a common problem, with 50% of women and 30% of men in Europe feel they have sensitive skin.

The Quantitative sensory testing (QST) is a physico-psychic method that uses gradients stimuli of different modalities to measure a subjective somatosensory response. This allows to characterize sensory dysfunction by assessing the participation of small and large nerve fibers.

The aim of this project is to characterize the presence or absence of a neurological disorder in patients with sensitive skin. This discovery would be a decisive argument to reinforce the suspicion that sensitive skins is linked to a small fiber neuropathy.

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Key information

Conditions

Age range

20 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

CHRU de Brest

Brest, 29200, France

About this study

Sensitive skin is a common problem, with 50% of women and 30% of men in Europe feel they have sensitive skin. A sensitive skin is characterized by the occurrence of tingling sensations, tightness, heat, burning, itching or pain triggered by non pathogenic factors such as wind, heat, cold, water , cosmetics, toiletries, stress...

The Quantitative sensory testing (QST) is a physico-psychic method that uses gradients stimuli of different modalities to measure a subjective somatosensory response. This allows to characterize sensory dysfunction by assessing the participation of small and large nerve fibers.

The aim of this project is to characterize the presence or absence of a neurological disorder in patients with sensitive skin. This discovery would be a decisive argument to reinforce the suspicion that sensitive skins is linked to a small fiber neuropathy.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age: between 20 and 60 years
  • Cooperating patient
  • Informed and written consent of the subject
  • Affiliated to the social security
  • For subjects with sensitive skin:

subjects with a score greater than 50 on the scale sensitive scale

  • To control subjects: subjects with result of less than 20 sensitive to the scale scale

Exclusion criteria

  • Adults subject with legal protection
  • Subject in a social institution.
  • Subject with major cognitive or psychiatric disorders
  • Subject with pathological use of alcohol or consumption of another drug.
  • Subject with skin involvement of the back of the dominant hand or malformation.
  • Known sensitive neuropathy
  • Pregnant woman
  • Subject receiving medical treatment which may interfere with the results.
  • Subject with treatment in the back of the dominant hand.

Treatment and study plan

Quantitative Sensory Testing

Device

Study of detection thresholds of vibration, cold and pain related to the heat in the dominant hand of the subjects through the QST.

Primary outcomes

  1. Cutaneous perception threshold

    Time frame: 6 months

    The cutaneous perception threshold of pain to heat.

Secondary outcomes

  1. The cutaneous perception threshold of vibration

    Time frame: 6 months

    The cutaneous perception threshold of pain to harm.

  2. The cutaneous perception threshold of cold

    Time frame: 6 months

    The cutaneous perception threshold of cold

Sponsors and collaborators

Lead sponsor

University Hospital, Brest

Other

Registry information

Acronym: SENSISKIN

Important dates

Study start
2017
Primary completion
2017
Study completion
2017
First posted
Mar 16, 2017
Registry last updated
Feb 4, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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