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NCT Number: NCT02855554

Quantitative Cardiac Parametric Mapping

The overall goal of this project is to evaluate the clinical potential of fast quantitative myocardial tissue characterization using recently emerged Cardiac Magnetic Resonance Imaging (CMR) techniques to aid the diagnosis, treatment, and follow up of patients with myocardial diseases, such as ischemic heart disease, cardiomyopathies, and myocarditis.

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Key information

Conditions

Cardiomyopathy, Myocarditis, Ischemic Heart Disease Cardiomyopathies Cardiovascular Diseases Heart Diseases Myocardial Ischemia Myocarditis Vascular Diseases

Age range

18 year–90 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Subject must be 18-90 years of age.
  • Subject must be previously diagnosed with or suspected to have one of the following conditions.
  • Myocardial ischemia or infarction (group 1)
  • Hypertrophic cardiomyopathy (group 2)
  • Infiltrative cardiomyopathy (group 3)
  • Myocarditis (group 4)
  • Subject must have been referred for a clinically indicated CMR.

Exclusion criteria

  • Subject has any implanted device or condition in which an MR scan would be contraindicated.
  • Subject has an acute psychiatric disorder or is cognitively impaired.
  • Subject is using or is dependent on substances of abuse.
  • Subject is unwilling to comply with the requirements of the protocol.
  • Subject has previously entered this study.
  • Subject has an allergy against MRI contrast agents.
  • Subject is in acute unstable condition.

Treatment and study plan

Cardiac Magnetic Resonance (CMR) imaging techniques

Other

Evaluation of clinical potential of fast quantitative myocardial tissue characterization using recently emerged CMRI techniques to aid the diagnosis, treatment, and follow up of patients with myocardial diseases.

Primary outcomes

  1. Clinical value of fast T1, T2, and T2* mapping of the left ventricle for the assessment of necrosis/scar, edema, and possible intramyocardial hemorrhage in patients with heart disease.

    Time frame: 2 years

Study contacts

Contact information is provided by the study sponsor or research team.

Jacob Rowe, BA

CONTACT

[email protected]

843-876-4922

Mark Ghent, BA

CONTACT

[email protected]

843-876-7148

Sponsors and collaborators

Lead sponsor

Medical University of South Carolina

Other

Registry information

Official study title

Novel Magnetic Resonance Imaging Techniques for Quantitative Cardiac Parametric Mapping

Acronym: Myomapping

Important dates

Study start
2014
Primary completion
2026
Study completion
2026
First posted
Aug 4, 2016
Registry last updated
Nov 5, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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