Quantification of the Time and Effort Required for Peripheral Blood Stem Cell Collection -The European Perspective

This non interventional study will consist of two parts:

I. Retrospective study:

A medical record review will be conducted covering 200 patients file undergoing peripheral blood stem cell mobilization in some European centers.

II. Prospective study :Time/Motion evaluation of actual apheresis - 20 events each center The actual apheresis events will be measured in consecutive patients scheduled to be candidates for peripheral blood stem mobilization in the apheresis area of the hospital. Each apheresis will be considered as one event . Should the patient receive more than 1 apheresis, each apheresis will be considered as one different event.

Inclusion criteria

Patients must satisfy the following for the part 1

• Oncology patients diagnosed with Non-Hodgkin lymphoma who are candidates for autologous hematopoietic stem cell transplantation (HSCT)
• A patient that fails to achieve a target CD34+>20 cells/µl, before or on the first day of apheresis
• Age > 18 years

Exclusion criteria

for the part 1

Patients with:

• Age < 18 years;
• Primary diagnosis other than Non-Hodgkin lymphoma
• Undergone prior autologous hematopoietic stem cell transplantation (HSCT)