Quantification of Motor Compensation Following Biomechanical, Proprioceptive and Physiological Alterations Post-lower Limb Amputation.

Inclusion criteria

• The patient must have given their free and informed consent and signed the consent form
• The patient must be a member or beneficiary of a health insurance plan
• Persons with unilateral transtibial or transfemoral amputees followed in the MPR department at the Nîmes University Hospital, RRL department, Grau du Roi University Rehabilitation Hospital.
• All etiologies: vascular, traumatic and septic.
• Adapted equipment validated by the rehabilitation doctor.
• Able to walk for 5 minutes on a treadmill without technical assistance

Inclusion criteria

specific to healthy volunteers:

• Adults (>18 years old) and under 40 years old
• Able to walk for 5 minutes on a treadmill without technical assistance.
• Body mass index between 18 and 25

Exclusion criteria

• The patient is participating in an interventional or a drug/medical device study, or is in a period of exclusion determined by a previous study
• The patient unable to express consent
• It is impossible to give the patient informed information
• The patient is under safeguard of justice or state guardianship
• Patient who has already been included in this study.
• Pregnant, parturient or breastfeeding patient.
• Appearance of a stump wound during the study requiring unloading.
• Patient for whom the implementation of vibration stimulation is not possible

Exclusion criteria

for amputee patients:

• Patient suffering from uncorrected or untreated visual disorders.
• Patient with major cognitive disorders (MoCA <23).
• Patient with vestibular disorders or uncontrolled epilepsy.
• Patient with an unhealed amputation stump.
• Patient with a weight > 135kg or < 20kg
• Patients with a FAC of 1 (i.e. patients who need firm and continuous assistance from a person to support their weight and maintain balance) or less.
• Sensory impairment that makes it impossible to perceive stimulation
• Significantly reduced bone density
• Patient in whom it is impossible to correctly adjust the GRAIL System harness to the corresponding body part due to:

• Body shape
• Colostomy bags
• Skin lesions that cannot be adequately protected.
• Any other reason that prevents a good, painless adjustment of the harness.
• Patient in whom it is impossible to correctly adjust the CON-TREX System:

• Body shape
• Colostomy bags
• Skin lesions that cannot be adequately protected.
• Any other reason that prevents a good, painless adjustment of the support systems.

Exclusion criteria

for healthy volunteers:

• History of significant injury or surgery affecting the lower limbs (such as hip or knee replacement or knee/ankle ligament reconstruction) that could impact walking
• History of neurological or psychiatric disorders that could affect locomotion or the processing of sensorimotor information.
• Drug treatments affecting locomotion: drugs likely to alter walking or balance, such as sedatives, muscle relaxants or neuroleptics.