Quantification of Human Adipogenesis

This pilot study is using a novel technology to measure the rate of turnover of new fat cells. Analysis of volunteer samples is ongoing, however the study is currently not enrolling new volunteers.

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Key information

Conditions

Healthy

Age range

18 year–49 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Aged 18-49 years.
Healthy.

Exclusion criteria

Significant chronic medical illness.
Illicit substance or alcohol abuse.
Body mass index > 27 kg/meters squared.
Underweight (BMI < 20 kg/m2).
History of keloid formation (excessive scarring).
Pregnant.

Treatment and study plan

15N-Thymidine, 2H-Water

Biological

Stable isotope 15N-thymidine, infused IV (15mg/hour) for 72 hours (phase 1 pilot).

Stable isotope 2H-water, ingested by mouth once per day for 3 days (phase 1 pilot) or 28 days (phase 2 pilot).

Primary outcomes

Quantifying human adipogenesis-counting the number of new fat cells.

Time frame: 4 weeks-7 months

Sponsors and collaborators

Lead sponsor

Brigham and Women's Hospital

Other

Registry information

Important dates

Study start: 2010
Primary completion: 2016
Study completion: 2017
First posted: Dec 10, 2010
Registry last updated: Jan 29, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed