Quality of Life, Nutritional Status and Functional Capacity in People With Advanced Chronic Kidney Disease

Kidney Disease and Quality of Life test (KDQOL-36). The generic component of the KDQOL-36 (items 1-12) is the SF-12, which allows obtaining 2 general scores: the Physical Component Summary (PCS) and the Mental Component Summary (MCS). The specific component of the KDQOL-36 (items 13-36), allows obtaining the scores of the specific subscales for the disease.

Self-Efficacy for Managing Chronic Disease test. The Self-Efficacy Scale for the Management of Chronic Diseases (SEMCD) is made up of 6 items on an analog scale, ranging from 1 (not at all sure) to 10 (totally safe).

The Spanish version (SEMCD-S) consists of 4 items. A higher number means greater self-efficacy. The scale score is the mean of the items.

Kidney Disease Knowledge Survey test. The Kidney Disease Knowledge Survey (KiKS) instrument consists of 28 items and aims to assess specific knowledge about chronic kidney disease in non-dialysis patients. One point is considered for each correct answer and zero for the incorrect one. The total score is calculated by adding all the correct points and divided by 28, obtaining a value from 0 to 1, with 1 being the highest level of knowledge.

Measured by body composition analysis

Weight in kg

Fat free body mass in kg assessed by bioelectrical impedance analysis

circumference in cm

circumference in cm

circumference in cm

serum potassium in mEq/l

serum phosphorus mg/dl

Calculated with the formula of CKD-EPI and MDRD and measured in ml/ min/ 1.73 m2

Serum albumin in g/dl

Serum prealbumin in mg/dl

Serum cholesterol in mg/dl

Serum HDL in mg/dl

Serum LDL in mg/dl

Serum TG in mg/dl

Plasma levels of high sensitivity C reactive protein (hs-CRP) in mg/dl

Blood count

Serum iron in μg/dl

Serum ferritin in ng/ml

Serum uric acid in mg/dl

Serum uric acid in mg/dl

Serum magnesium in mg/dl

Serum calcium in mg/dl

Serum intact parathyroid hormone (PTHi) in pg/ml

Serum vitamin D in ng/ml

Measured as HbA1c (glycated hemoglobin)

HADS depression and anxiety symptoms screening test. It is a self-administered scale with 14 items divided into 2 subscales (anxiety and depression) whose maximum score is 21 points for each of them. Based on the score obtained, the patients can be classified as normal (<7), doubtful (between 8 and 10) and potential clinical case (≥ 11). The score is referred to the last week.

Scale of autonomy for activities of daily life "Barthel test". This test measures the capacity of the person to carry out ten basic activities of daily life, obtaining a quantitative estimate of the degree of dependence of the subject. The range of possible IB values is between 0 and 100, with 5-point intervals for the original version. The closer a subject's score is to 0, the more dependency they have; the closer to 100 the more independence.

Physical activity test "Short Physical Performance Battery" SPPB. This in turn includes 3 tests: balance, gait speed and getting up and sitting in a chair 5 times. Each test is scored from 0 (worst performance) to 4 (best performance): for the balance test according to a hierarchical combination of performance in the 3 component subtests and for the other 2 tests a score of 0 is assigned to those who do not complete or they attempt the task and scores from 1 to 4 based on the time spent. In addition, a total score for the entire battery is obtained, which is the sum of the 3 tests and ranges from 0 to 12.

The International Physical Activity Questionnaire (IPAQ) will be used to evaluate the current physical activity level of the participants. The survey consists of 27 questions and 5 parts.

Strength will be recorded by Jamar Hydraulic Hand Dynamometer (Kg)

International Physical Activity Questionnaire (IPAQ). The IPAQ consists of 7 questions about the frequency, duration and intensity of activity (moderate and intense) carried out in the last seven days, as well as walking and sitting time in a work day. It evaluates three characteristics of physics (PA): intensity (mild, moderate or vigorous), frequency (days per week) and duration (time per day). Weekly activity is recorded in Mets (Metabolic Equivalent of Task or Metabolic Index Units) per minute and week.

Handgrip strength in kg, measured by the jamar hydraulic hand dynamometer.

Assess if syastolic and diastolic pressure improves after training and at 6 months of follow-up.

Adherence to the Predimed Plus diet pattern 17 (0 - minimum adherence, 17 - maximum adherence)