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NCT Number: NCT07427901

Quality Of Life In Colorectal Cancer Survivors

The purpose of this study is to identify late adverse effects in colorectal cancer patients that may influence quality of life at 6, 12, and 24 months after oncological treatment. The study aims to assess quality of life in colorectal cancer survivors in relation to psycho-physical-social well-being at different time points and to evaluate the prevalence of late adverse effects and their association with diagnosis and specific oncological treatment.

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Key information

Conditions

Colorectal Cancer Colon Cancer Colonic Diseases Colonic Neoplasms Colorectal Neoplasms Digestive System Diseases Digestive System Neoplasms Gastrointestinal Diseases Gastrointestinal Neoplasms Intestinal Diseases Intestinal Neoplasms Neoplasms Neoplasms by Site Rectal Cancer Rectal Diseases Rectal Neoplasms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

About this study

The purpose of this study is to identify late adverse effects in patients with colorectal cancer that may influence quality of life at 6, 12, and 24 months after oncological treatment. The study will assess quality of life in colorectal cancer patients in relation to psycho-physical-social well-being at different time points. In addition, the study will identify and evaluate the prevalence of late adverse effects and analyze their association with diagnosis and specific oncological treatment.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with colorectal cancer (colon or rectal cancer)
  • Age 25 to 65 years
  • First oncological treatment performed at the Institute of Oncology Ljubljana
  • Working-capable patients
  • Ability to complete questionnaires
  • Ability to provide written informed consent

Exclusion criteria

  • Age < 25 years or > 65 years
  • Patients unable to complete questionnaires
  • Patients unable to participate in follow-up assessments
  • Patients who do not provide written informed consent

Treatment and study plan

Quality of Life Assessment

Other

Quality of life assessment using questionnaires at 6, 12, and 24 months after oncological treatment.

Primary outcomes

  1. Quality of Life Score (EORTC QLQ-C30 Global Health Status/QoL Scale)

    Time frame: 6, 12, and 24 months after oncological treatment

    Quality of life will be assessed using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30), specifically the Global Health Status/Quality of Life scale (items 29 and 30). Scores will be linearly transformed to a 0 to 100 scale. Higher scores indicate better quality of life.

Secondary outcomes

  1. Colorectal Cancer-Specific Quality of Life (EORTC QLQ-CR29)

    Time frame: 6, 12, and 24 months after oncological treatment

    Colorectal cancer-specific quality of life will be assessed using the EORTC QLQ-CR29 questionnaire. Scores will be linearly transformed to a 0 to 100 scale. Higher scores indicate better functioning for functional scales and worse symptoms for symptom scales.

Study contacts

Contact information is provided by the study sponsor or research team.

Klavdija Korošec

CONTACT

[email protected]

+386 31630065

Neža Gros

CONTACT

[email protected]

Sponsors and collaborators

Lead sponsor

Institute of Oncology Ljubljana

Other

Registry information

Important dates

Study start
2023
Primary completion
2024
Study completion
2027
First posted
Feb 23, 2026
Registry last updated
Feb 23, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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