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Recruiting

NCT Number: NCT07186699

Qualitative Study on Detection & Tx of NSCLC in Pts w/ a History of Alcohol or SUD

This study will attempt to identify social facilitators and barriers to detection and treatment of non-small cell lung cancer in order to learn how a history of substance abuse or alcohol use impacts care for non-small cell lung cancer.

Recruiting

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Los Angeles General Medical Center, Los Angeles, California, United States

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About this study

PRIMARY OBJECTIVE:

I. To identify social facilitators and barriers to detection and treatment of NSCLC by interviewing a diverse group of patients at Keck, Los Angeles General Medical Center, and Norris Cancer Center with alcohol or substance use disorder history.

OUTLINE: This is an observational study.

Patients participate in a semi-structured interview and may participate in a follow-up focus group interview in which preliminary findings are shared and feedback is elicited on study.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • * Adults ≥ 18 years of age
  • Histopathologic or cytologic diagnosis of NSCLC
  • Received or receiving curative intent treatment (e.g. surgery, radiation therapy, systemic therapy)
  • History of alcohol use or substance use disorder (other than tobacco use disorder) within the past 10 years, predating the cancer diagnosis
  • Ability to understand and the willingness to sign a written informed consent
  • English or Spanish speaking. Due to need to conduct semi-structured interviews which can develop into free-flowing conversations we need both participant and interviewer to be fluent

Exclusion criteria

  • Patients with cognitive disability unable to maintain 30-60 minute conversation

Treatment and study plan

Non-Interventional Study

Other

Non-interventional study

Other names: Non-Interventional Observational Study, Noninterventional (Observational) Study

Primary outcomes

  1. Thematic saturation

    Time frame: Up to 3 years

    Will use a Danaher framework to approach analyze interview data using NVivo software (NVivo version 11.0, QSR International). Each interview will be analyzed to identify broad themes.

Sponsors and collaborators

Lead sponsor

University of Southern California

Other

Collaborators

  • National Cancer Institute (NCI)

Registry information

Official study title

Qualitative Study on Detection and Treatment of Non-Small Cell Lung Cancer in Patients With a History of Alcohol or Substance Use Disorder

Important dates

Study start
2025
Primary completion
2027
Study completion
2028
First posted
Sep 22, 2025
Registry last updated
Apr 2, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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