Qishenyiqi for Ventricular Remodeling After Myocardial Infarction

Inclusion criteria

• 1) The history of acute myocardial infarction exceeds 3 months;
• 2) Symptoms and signs of heart failure have been stable for more than one month;
• 3) 18 years old or more;
• 4) NYHA cardiac function classified as grade II~IV;
• 5) LVEF≤40%；
• 6) NT-proBNP≥450pg/ml；
• 7) All subjects or their guardians must sign the subject consent before entering the trial.

Exclusion criteria

• 1) Patients with the following diseases: nonischemic cardiomyopathy; valvular heart disease; congenital heart disease; obstruction of left ventricular outflow tract; severe decompensated heart failure; active myocarditis or pericardial disease; end-stage liver and kidney diseases; malignant tumor;
• 2) Planned to undergo cardiac surgery within 12 months;
• 3) Mechanical complications of myocardial infarction;
• 4) Pregnant or nursing, or having the intention to give birth within one year;
• 5) Patients who participated in clinical research of other drugs within 3 months before being selected;
• 6) Patients with poor sound transmission windows are examined by transthoracic ultrasound.