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NCT Number: NCT02662270

QEEG and Qualitative EEG for the Identidification of Abnormal Patterns in Fibromyalgia Patients

Fibromyalgia is a relatively young condition recently recognized by the WHO as a separated clinical entity. Part of the medical comunity thinks of it as a mixed condition between depresion and rheumatic pain, however, functional data provided by sophisticated imaging techniques points at a diminished brain activity in several brain regions. The present study aims to characterize those findings by means of QEEG in order to establish the electroencephalographic characteristics of fibromyalgia patients.

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Key information

Conditions

Fibromyalgia Disease Muscular Diseases Musculoskeletal Diseases Nervous System Diseases Neuromuscular Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Rheumatic Diseases

Age range

20 year–70 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Universidad de Murcia

Murcia, Spain

About this study

Fibromyalgia is a disease that part of the general population and even the medical community views with skepticism and only recently was accepted as a true condition by the World Health Organization. Some physicians see it as a form of depresion mixed with rheumatic pain. However recent findings in functional magnetic resonance imaging and positron emited tomography documented diminished brain activity on several regions. The impairments must be located within the areas with a documented functional defect, wherein, spontaneous braincells activity chould arise. Therefor electroencephalography findings should be a valuable diagnostic tool for early detection in fibromyalgia. The present study aims to analyse the differences between bioelectric characteristics in EEG from fibromyalgia patients with their eyes closed in a 21 electrode arragement. Normal graphoelements as well as abnormal ones and its topographic distribution and functional conections will be analyzed.

The working hypotesis is that fibromyalgia patients will present distintive characteristics in the same areas where a diminished brain activity has been documented by metabolic and morphologic tests as a group and that those characteristics are suitable to be measured by QEEG and distinguishable from healthy subjects.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Men and women between 20 and 70 years old, diagnosed with fibromyalgia and a control group matched by age and gender

Exclusion criteria

  • Any other concomitant neurologic disease or impairment

Treatment and study plan

Primary outcomes

  1. Differences between groups in Fast Fourier Transformation

    Time frame: Up to one year

    Changes in Power in EEG over different electrodes

  2. Topographic distribution of the frequency bands

    Time frame: Up to one year

    Brain areas with a characteristic pattern

  3. Dominant EEG frequency localization

    Time frame: Up to one year

    To document the dominant frequency in the resting EEG for all subjects

  4. Abnormal EEG-graphoelements description

    Time frame: Up to one year

    To identify the abnormal EEG-graphoelements found in fibromyalgia patients

  5. Functional conectivity

    Time frame: Up to one year

    To identify the different brain connections between fibromyalgia patients

Sponsors and collaborators

Lead sponsor

Spanish Foundation for Neurometrics Development

Other

Collaborators

  • Universidad de Murcia

Registry information

Official study title

Quantitative and Qualitative EEG From Fibromyalgia Patients for the Identification of Abnormal Patterns on Closed Eyes EEG

Acronym: QEEGFP

Important dates

Study start
2022
Primary completion
2023
Study completion
2023
First posted
Jan 25, 2016
Registry last updated
Aug 2, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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